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Record W4394929928 · doi:10.1093/jbcr/irae036.162

527 Combination Treatment for Hypertrophic Burn Scars Utilizing Fractional Ablative and Continuous Wave CO2 Laser

2024· article· en· W4394929928 on OpenAlexaboutno aff
P. W. R. Lee

Bibliographic record

VenueJournal of Burn Care & Research · 2024
Typearticle
Languageen
FieldMedicine
TopicDermatologic Treatments and Research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineAblative caseHypertrophic scarsScarsLaser therapySurgeryLaserDermatologyOptics

Abstract

fetched live from OpenAlex

Abstract Introduction Hypertrophic scars remain a devastating consequence of severe burn wounds, producing anatomic deformities, as well as functional impairment. Fractional ablative CO2 laser treatment has shown scar - reducing effects. In this study, we compared the outcomes of combining two different CO 2 lasers or fractional ablative CO2 laser alone in treating hypertrophic burn scars. Methods Forty patients with hypertrophic burn scars were included in one of following two groups: fractional ablative CO2 laser combined with continuous wave CO2 laser (group 1) or fractional ablative CO2 laser alone (group 2). Three plastic surgeons rated the hypertrophic scars according to observer-rated Vancouver Scar Scale (VSS) before and after treatment (at least 6 months after the last laser) and by patient-completed questionnaires after treatment (at least 6 months after the last laser). Results Forty patients completed the laser treatment. Group 1 showed significant improvement in vascularity, pliability, and height than group 2 (p < 0.05) but not in pigmentation. Time-dependent analysis of total VSS scores suggested that group 1 experienced more improvement during a shorter treatment period than group 2 (p < 0.05). For patient-reported outcomes, group 1 showed significant improvement than group 2 in scar appearance, scar thickness, pain, and pruritus (p < 0.05). Conclusions Observer-reported VSS outcomes showed that combining laser treatment resulted in more improvement of vascularity, pliability, and height indices for hypertrophic burn scars. Patient-completed outcomes showed that combining laser therapy was considered more helpful for improving scar appearance, scar thickness, pain, and pruritus than fractional ablative laser alone. Furthermore, combination treatment appeared to produce more improvement in a shorter period of time. Applicability of Research to Practice The two lasers are widely used in scar treatment in South Korea, so yes this research can be applied to medical practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.106
GPT teacher head0.420
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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