0367 The Independent and Interactive Effects of Insomnia Symptoms and Short Sleep on Sleep Physiology
Bibliographic record
Abstract
Abstract Introduction The presence of subjective insomnia complaints with objective short sleep duration (total sleep time [TST] < 6 hours/night) has been associated with more severe health outcomes compared to insomnia or shortened sleep alone. The differential and possibly interacting effects of insomnia and shortened sleep on sleep physiology have not yet been comprehensively characterized. Methods 1,014 participants from the Sleep Apnea Global Interdisciplinary Consortium (SAGIC) without sleep apnea (apnea-hypopnea index < 5 events/hour) were included. Participants were categorized as having insomnia or good sleepers based on self-reported symptoms and as short (< 6 hours/night) or normal (≥6 hours/night) sleepers based on in-laboratory TST. Analysis of variance models adjusted for age and sex assessed the effects of insomnia, shortened sleep, and their interaction on traditional sleep architecture (percent of TST in each sleep stage), EEG power metrics, and novel odds ratio product (ORP; indexes sleep depth ranging from 0 [deep sleep] to 2.5 [full wakefulness]) metrics (average ORP in each sleep stage and ORP-9 [speed with which sleep deepens following arousal]). Results Neither insomnia status, sleep duration, nor their interaction had significant effects on the percent of TST spent in any sleep stage. The interaction between insomnia status and sleep duration was not significant for any ORP or EEG metrics. However, individuals with insomnia demonstrated lighter sleep (higher NREM ORP [p=0.02, η2=0.01], REM ORP [p =0.002, η2=0.02], and ORP-9 [p=0.0002, η2=0.03]), cortical hyperarousal (higher beta power in 14-20 Hz [p=0.0003, η2=0.03] and 20-35 Hz [p=0.001, η2=0.02]), and higher sigma power (12-16 Hz [p=0.04, η2=0.01]) compared to good sleepers. Short sleepers also demonstrated lighter REM sleep (higher ORP [p=0.0004, η2=0.03]) and cortical hyperarousal (higher beta power in 14-20 Hz [p< 0.0001, η2=0.04] and 20-35 Hz [p< 0.0001, η2=0.04]) as well as lower delta power (1-4 Hz [p=0.0009, η2=0.02]) and theta power (4-7 Hz [p< 0.0001, η2=0.05]) relative to normal sleepers. Conclusion While insomnia and shortened sleep did not influence traditional sleep architecture, they were differentially associated with alterations in sleep physiology. These more granular metrics may be useful in future investigations of potentially separable mechanisms that underlie adverse health consequences in insomnia versus shortened sleep. Support (if any)
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.006 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.002 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.013 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".