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Record W4395059637 · doi:10.5206/uwomj.v89i2.10482

Mothballs, status dystonicus and critical care: an unusual case of G6PD deficiency

2021· article· en· W4395059637 on OpenAlexvenueno aff
Timothy Varghese, Rishi Ganesan

Bibliographic record

VenueUniversity of Western Ontario Medical Journal · 2021
Typearticle
Languageen
FieldMedicine
TopicRestraint-Related Deaths
Canadian institutionsnot available
Fundersnot available
KeywordsMedicine

Abstract

fetched live from OpenAlex

Glucose 6 Phosphate Dehydrogenase (G6PD) is a critical enzyme in the pentose phosphate pathway, a pathway that acts to provide reducing energy to cells. G6PD deficiencies are X-linked inherited disorders, in which the G6PD on red blood cells (RBCs) is defective. This case report will focus on an G6PD deficient individual of Thai descent, Sill, who was exposed to moth balls at an early age. The damage left him with severe dystonic Cerebral Palsy (CP), a permanent movement disorder, causing him to constantly display asymmetric posturing and opisthotonic movements. This article follows Sill through his admission, initially for GJ Tube re-insertion, then for hypoxemia. Sill is seen by several services, who attempt various forms of medication and procedures. This case ends with the insertion of an Intrathecal Baclofen pump; a potential remedy for Sill's current symptoms. Lastly, we discuss the implications of screening for conditions that are typically benign, such as G6PD deficiencies, but can have lethal outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.052
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.276
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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