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Record W4395478232 · doi:10.21203/rs.3.rs-4258984/v1

The national and sub-national patterns of age of menopause and its associated factors: An experience from Iran STEPS Survey 2021

2024· preprint· en· W4395478232 on OpenAlexaff
Shirin Djalalinia, Yosef Farzi, Golaleh Almasi, Sina Azadnajafabad, Naser Ahmadi, Nazila Rezaei, Ameneh Kazemi, Negar Rezaei, Arezou Dilmaghani‐Marand, Moein Yoosefi, Mohammad‐Mahdi Rashidi, Erfan Ghasemi, Ali Golestani, Elham Abdolhamidi, Maryam Nasserinejad, Amirali Hajebi, Rosa Haghshenas, Sahar Mohammadi Fateh, Kamyar Rezaee BSc, Arefeh Alipour Derouei, Sahar Saeedi Moghaddam, Marziyeh Vahid Dastjerdi, Bagher Larijani, Fahimeh Ramezani Tehrani, Farshad Farzadfar

Bibliographic record

VenueResearch Square · 2024
Typepreprint
Languageen
FieldMedicine
TopicMenopause: Health Impacts and Treatments
Canadian institutionsMemorial University of Newfoundland
FundersMinistry of Health and Medical EducationNational Institute for Health and Care ResearchWorld Health Organization
KeywordsMenopauseMedicineSurgical MenopauseNational Health and Nutrition Examination SurveyGerontologyDemographyGynecologyEnvironmental healthPopulationInternal medicine

Abstract

fetched live from OpenAlex

Abstract Background: Menopause as an important health issue needs special attention and planning to provide extensive services and interventional programs to manage the complications and adverse health consequences. Benefiting from a national and sub-national representative sample, the present study aimed to estimate the distribution of age of menopause and its associated factors in Iranian women. Methods: Present investigation was a part of the national survey of non-communicable disease risk factor surveillance (STEPS 2021) in Iran. Through a systematic random sampling, under safety considerations during the COVID-19 pandemic, of the 28,520 adults who were found to be in included in the survey, 27,874 participants completed the questionnaires (step 1), 27,745 individuals were anthropometrically measured (step 2), and 18,119 individuals completed laboratory evaluation (step 3). Present study included 13291 females who had non-missing menopause values. Menopause before the age of 45 years is considered "early menopause". Theovarian failure/surgical removal of the ovaries before the age of 40 years as; "premature ovarian insufficiency". The others group were; normal (40-50), and late (55 ≤) menopause. Results: In 2021, 28.58% (95% CI: 27.67, 29.48) of 25≤ year-old Iranian women were menopause. In adult menopause, the prevalence of early menopause was 4.55% (3.88,5.22) and 11.63% (10.64,12.63) had late menopause. Based on the sub-national distribution of age of menopause; early menopause was the dominant pattern in the most of eastern provinces. The low physical activity, significantly decreased the age-adjusted Odds ratio of menopause (p< 0.05). The current smoking and hookah consumption, as well as the history of continuous smoking, were significantly associated to the decreasing in age-adjusted OR of the age of menopause (p< 0.05). These significant association also detected in widow marriage status participants; women with public sector employment and who had more than 12 years of schooling (p< 0.05). Conclusion: The findings of present study could be used for promotion of health planning and interventions at national and sub-national levels. Special attentions need for early monitoring of women with a family history of early menopause, especially, who have life style risk factors. Consequently, special attention should be considered to probable factors confounding menopause age among Iranian women.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.040
Threshold uncertainty score0.079

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.254
GPT teacher head0.480
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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