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Record W4396513780 · doi:10.1093/pnasnexus/pgae175

Human-aided dispersal and population bottlenecks facilitate parasitism escape in the most invasive mosquito species

2024· article· en· W4396513780 on OpenAlexaff
Maxime Girard, Edwige Martin, Laurent Vallon, Van Trân Van, Camille Da Silva Carvalho, Justine Sack, Zélia Bontemps, Julie Balteneck, Florence Colin, Pénélope Duval, Simon Malassigné, Ian Hennessee, Lucrecia Vizcaino, Yamila Romer, Nsa Dada, Khan Ly Huynh Kim, Trang Huynh Thi Thuy, Christophe Bellet, Grégory L’Ambert, Fara Nantenaina Raharimalala, Natapong Jupatanakul, Clément Goubert, Matthieu Boulesteix, Patrick Mavingui, Emmanuel Desouhant, Patricia Luis, Rémy Cazabet, Anne‐Emmanuelle Hay, Claire Valiente Moro, Guillaume Minard

Bibliographic record

VenuePNAS Nexus · 2024
Typearticle
Languageen
FieldMedicine
TopicMosquito-borne diseases and control
Canadian institutionsMcGill UniversityMcGill Genome Centre
FundersOffice of National Higher Education Science Research and Innovation Policy CouncilAgence Nationale de la RechercheEmory University
KeywordsBiological dispersalBiologyAedes albopictusInvasive speciesEcologyParasitismPopulationParasite hostingRange (aeronautics)Introduced speciesVector (molecular biology)LarvaZoologyHost (biology)Aedes aegypti

Abstract

fetched live from OpenAlex

Abstract During biological invasion process, species encounter new environments and partially escape some ecological constraints they faced in their native range, while they face new ones. The Asian tiger mosquito Aedes albopictus is one of the most iconic invasive species introduced in every inhabited continent due to international trade. It has also been shown to be infected by a prevalent yet disregarded microbial entomoparasite Ascogregarina taiwanensis. In this study, we aimed at deciphering the factors that shape the global dynamics of A. taiwanensis infection in natural A. albopictus populations. We showed that A. albopictus populations are highly colonized by several parasite genotypes but recently introduced ones are escaping it. We further performed experiments based on the invasion process to explain such pattern. To that end, we hypothesized that (i) mosquito passive dispersal (i.e. human-aided egg transportation) may affect the parasite infectiveness, (ii) founder effects (i.e. population establishment by a small number of mosquitoes) may influence the parasite dynamics, and (iii) unparasitized mosquitoes are more prompt to found new populations through active flight dispersal. The two first hypotheses were supported as we showed that parasite infection decreases over time when dry eggs are stored and that experimental increase in mosquitoes’ density improves the parasite horizontal transmission to larvae. Surprisingly, parasitized mosquitoes tend to be more active than their unparasitized relatives. Finally, this study highlights the importance of global trade as a driver of biological invasion of the most invasive arthropod vector species.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.288
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2024
Admission routes1
Has abstractyes

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