COMBINED AMNIOTIC MEMBRANE GRAFT AND AUTOLOGOUS RETINAL TRANSPLANT FOR REPAIR OF REFRACTORY CHRONIC MYOPIC MACULAR HOLES
Bibliographic record
Abstract
PURPOSE: The objective of this study was to report a technique for reconstruction of large, persistent, chronic, myopic macular holes using a combined human amniotic membrane graft and autologous retinal transplant. METHODS: Three patients with large, myopic macular holes who failed prior surgical attempts and underwent subretinal amniotic membrane graft with overlying autologous retinal transplant and short-term perfluorocarbon tamponade were included in this study. Preoperative and postoperative visual acuity and images were analyzed at 3, 6, and 9 months. RESULTS: All three myopic macular holes remained closed at 9 months with resolution of central scotoma. The first case, a 69-year-old woman, presented with a persistent macular hole whose minimum linear diameter was 1,085 µm. Her preoperative visual acuity of 20/200 improved by 9 months to 20/100. Second, a 72-year-old man with a history of recurrent retinal detachment repair with silicone oil and persistent macular hole of 1,134 µm presented with preoperative visual acuity of 20/200, which was unchanged at 9 months. Finally, a 76-year-old woman with a persistent macular hole of 935 µm with preoperative visual acuity of 20/80 improved by 9 months postoperative to 20/50. No complications were encountered related to the grafts. CONCLUSION: Combined amniotic membrane graft and autologous retinal transplant may provide a surgical option for repair of refractory, large, chronic myopic macular holes with underlying atrophy.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".