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Record W4396695882 · doi:10.1038/s44161-024-00471-7

Primitive macrophages induce sarcomeric maturation and functional enhancement of developing human cardiac microtissues via efferocytic pathways

2024· article· en· W4396695882 on OpenAlexafffund
Homaira Hamidzada, Simon Pascual‐Gil, Qinghua Wu, G Kent, Stéphane Massé, Crystal Kantores, Uroš Kuzmanov, Marta Gómez-Garcı́a, Naimeh Rafatian, Renée A. Gorman, Marianne Wauchop, Wenliang Chen, Shira Landau, Tasnia Subha, Michael Atkins, Yimu Zhao, Erika L. Beroncal, Ian Fernandes, Jared Nanthakumar, Shabana Vohra, Erika Y. Wang, Tamilla Valdman Sadikov, Babak Razani, Tracy L. McGaha, Ana C. Andreazza, Anthony O. Gramolini, Peter H. Backx, Kumaraswamy Nanthakumar, Michael A. Laflamme, Gordon Keller, Milica Radisic, Slava Epelman

Bibliographic record

VenueNature Cardiovascular Research · 2024
Typearticle
Languageen
FieldMedicine
TopicTissue Engineering and Regenerative Medicine
Canadian institutionsPrincess Margaret Cancer CentreYork UniversityStem Cell NetworkUniversity Health NetworkToronto General HospitalUniversity of TorontoTed Rogers Centre for Heart Research
FundersNational Institute of Diabetes and Digestive and Kidney DiseasesNational Heart, Lung, and Blood InstituteCanadian Institutes of Health ResearchHospital for Sick ChildrenGovernment of CanadaNational Institutes of HealthStem Cell Network
KeywordsCell biologyBiologyChemistry

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.341
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations55
Published2024
Admission routes2
Has abstractno

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