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Record W4396746895 · doi:10.21203/rs.3.rs-4340349/v1

Initiatives to promote uptake and adherence to Option B+ program among rural pregnant women living with HIV in Malawi

2024· preprint· en· W4396746895 on OpenAlexaff
Emmanuel Chilanga, Ruth Agather Mbeya

Bibliographic record

VenueResearch Square · 2024
Typepreprint
Languageen
FieldMedicine
TopicHIV/AIDS Research and Interventions
Canadian institutionsUniversity of Northern British Columbia
Fundersnot available
KeywordsHuman immunodeficiency virus (HIV)MedicineEconomic growthEnvironmental healthBusinessObstetricsSocioeconomicsFamily medicineEconomics

Abstract

fetched live from OpenAlex

Abstract Background Malawi is the first country in the world to introduce Option B+, a test-and treat program for preventing vertical transmission of HIV from mothers to young children during pregnancy or breastfeeding. The program has significantly reduced the number of children that contract HIV from their mothers. Although this is the case, gaps remain as the program is marred with challenges such as clients opting out, low drug adherence, and default. This study examines the effectiveness of individual and community level approaches used to promote uptake of Option B+ program through reduction of intimate partner violence (IPV) in central Malawi. Methods A retrospective narrative qualitative research method was used to understand strategies that HIV positive pregnant women and community stakeholders used to improve uptake of Option B+ program. Twenty-five participants that were directly involved in Option B+ program as beneficiaries and service providers were interviewed. The interviews were audio recoded and transcribed verbatim. Data was manually coded to derive key themes and concepts. Results Prevalent forms of IPV against HIV pregnant mothers during initial stage of Option B+ program was identified. They include husband restricting women from taking Antiretroviral Therapy (ART), declining the use of condoms, and reducing family support. Various risk-taking behaviours was used to minimize IPV when some pregnant women were diagnosed HIV positive. These include opting out of the program, concealing the HIV serostatus and ART drugs. The integration of community based reproductive health initiatives such as expert clients, male championship, and safe motherhood into Option B+ program reduced cases of IPV and improved couple uptake of HIV testing. Conclusion Integration of Option B+ program with community based reproductive health promotion initiatives has a potential of reducing IPV against HIV positive pregnant women. The strategy can also increase the number of couples that can adopt Option B+ program in rural communities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.020
Threshold uncertainty score0.040

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0010.003
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.428
Teacher spread0.368 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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