Short-term antenatal corticosteroid increases risk of respiratory morbidity in late preterm infants
Bibliographic record
Abstract
Background/Aim: Although antenatal corticosteroid (ANCS) is beneficial for preventing respiratory distress in preterm infants, the effect of ANCS on late preterm infants (LPI) is still unknown. This study aimed at investigating the effect of ANCS on respiratory morbidity of LPI. Materials and Methods: In matched cohort study, LPI of mothers who received ANCS (ANCS group) at 24–34 weeks of GA were matched with LPI of no ANCS (non-ANCS group) by gestational age and birth weight. Results: During 2 years, the ANCS group was 10.6% (191/1,810) in LPI and only 177 neonates met the criteria for inclusion and were ANCS group. The mean gestational age was 34.6 ± 0.7 weeks in both groups. Birth weights were 2270 ± 405 g and 2265 ± 401 g in ANCS and non-ANCS groups, respectively. Of the 177 infants whose mothers received ANCS, overall respiratory morbidities were 31.6% comparing to 30.5% in non-steroid group. Although decrease trend toward of RDS (4% vs. 8.5%, P = 0.07) and surfactant administration (3.4% vs. 6.2%, P = 0.21) was observed in steroid group, administration of steroid < 24 h before gestation significantly increase RDS compared with non-treatment (33.3% vs. 8.5%, P = 0.04). Conclusions: ANCS did not decrease risk of respiratory morbidity. Nevertheless, treatment with ANCS for a short period (<24 h) may increase RDS in LPI.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.005 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".