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Record W4396855279 · doi:10.21203/rs.3.rs-4343298/v1

Comparison of Canadian online pharmacies with conventional pharmacies for erectile dysfunction drugs. The Cost of Convenience and discretion

2024· preprint· en· W4396855279 on OpenAlexaffabout
Michael Morra, Harliv Dhillon, Premal Patel

Bibliographic record

VenueResearch Square · 2024
Typepreprint
Languageen
FieldMedicine
TopicSexual function and dysfunction studies
Canadian institutionsUniversity of Manitoba
Fundersnot available
KeywordsPharmacyMedicineErectile dysfunctionFamily medicineAdvertisingDiscretionMedical prescriptionPillOrder (exchange)BusinessMarketingFinancePsychiatryNursing

Abstract

fetched live from OpenAlex

<title>Abstract</title> <bold>Introduction</bold> Erectile dysfunction (ED) is a common condition affecting about 50% of men over the age of 40. ED can be related to cardiovascular disease and diabetes requiring further evaluation and workup, unfortunately many men with ED commonly avoid seeking treatment for reasons such as embarrassment. In the past few years, multiple online pharmacies offering easy access to ED medications have emerged, advertising easy online forms, no conventional doctors visit and discreet delivery to their home. We sought to compare the prices of five popular online ED pharmacies with conventional pharmacies, hypothesizing that online pharmacies would come at increased cost to patients. <bold>Methods</bold> The five online pharmacies were found on the first result page of a google search for “ED drugs online Canada”. Consumer prices for Tadalafil and Sildenafil were acquired through available website information or by contacting customer service. The prices were expressed as price per pill and compared with four conventional pharmacies in Winnipeg, Manitoba. Pricing differences were expressed as a percentage. <bold>Results</bold> When comparing the price per pill of the smallest order of tabs that can be purchased, the price of ED medications from online pharmacies was on average 15% higher without including the dispensing fee of the conventional pharmacy comparators. Once taking dispensing fees into account, the cost ED medications from conventional pharmacies was about 3-4% higher compared to online conventional pharmacies. Dispensing fees ranged from $12.99 to $16.00 per order. Savings could be seen with conventional pharmacies when order quantities increased as the dispensing fee is fixed per order. <bold>Conclusions</bold> Online pharmacies in Canada that boast convenience and discretion to customers offer similar pricing to conventional pharmacies. Despite their competitive pricing, their focus on discretion further perpetuates common stereotypes of ED that may prevent men from seeking help from their care providers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.373
Threshold uncertainty score0.995

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.218
GPT teacher head0.495
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes2
Has abstractyes

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