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Record W4397041002 · doi:10.1681/asn.20233411s11089b

Dialysis-Associated Peritonitis due to Serratia marcescens: A Case Report

2023· article· en· W4397041002 on OpenAlexaboutno aff
Alejandro Toledo Carranza

Bibliographic record

VenueJournal of the American Society of Nephrology · 2023
Typearticle
Languageen
FieldMedicine
TopicDialysis and Renal Disease Management
Canadian institutionsnot available
Fundersnot available
KeywordsSerratia marcescensMedicinePeritonitisPeritoneal dialysisIntensive care medicineDialysisInternal medicineMicrobiologyBiologyEscherichia coli

Abstract

fetched live from OpenAlex

Introduction: Serratia marcescens (SM) is a Gram-negative, opportunistic, highly virulent bacterium and a rare pathogen that causes peritonitis Case reports, a Canadian case series, and a systematic review in Hong Kong suggested that peritonitis in PD due to SM was associated with high rates of treatment failure and catheter removal We present a clinical case of peritonitis due to SM that led to catheter loss. Case Description: A 34-year-old man with a history of end-stage renal disease secondary to diabetes on continuous ambulatory PD for 5 years with a history of 2 previous cases of peritonitis with adequate resolution of these and with peritoneal fluid (PF) cultures without microorganism development Admitted for severe abdominal pain, nausea, vomiting and diarrhea in addition to cloudy PF cytology was requested where leukocytes were “uncountable”, being 100% polymorphonuclear (PNL), empirically started intravenous ceftriaxone and vancomycin; PF culture was collected where SM was isolated, treatment was continued and cytology was taken again on the third day of treatment finding leukocytes of 1130, being 90% PNL, thinking in adequate response antibiotics were continued for 7 days, however, he presented fever, cytology reporting 3456 leukocytes with 90% of PNL and new culture with isolation of SM again, showing sensitivity to meropenem by meropenem, showing sensitivity to meropenem by meropenem, and the patient was treated with a new culture, She showed sensitivity to meropenem, so it was decided to change the antibiotic, which was effective for 3 days until she presented clinical deterioration and a referral to nephrology was requested, who decided to change to HD and remove the catheter, during the removal she presented purulent material and multiple adhesions, so it was decided that the cavity was not useful and definitive HD; She completed 14 days of treatment with meropenem, presenting improvement and it was decided to discharge her. Discussion: Peritonitis due to SM is a serious complication, so its surveillance should be intensified and appropriate treatment compatible with the antibiogram should be offered. Low socioeconomic status, poor home environment and hygienic conditions increase the rates of peritonitis due to this pathogen, so more frequent and careful patient and family education in such conditions may improve patient care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0040.002
Science and technology studies0.0040.002
Scholarly communication0.0030.004
Open science0.0020.003
Research integrity0.0060.004
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.291
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2023
Admission routes1
Has abstractyes

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Same venueJournal of the American Society of NephrologySame topicDialysis and Renal Disease ManagementFrench-language works237,207