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Record W4399418737 · doi:10.21203/rs.3.rs-4462114/v1

Comparative Effectiveness of Minimally Invasive Surgery vs Open Surgery in neuroblastoma

2024· preprint· en· W4399418737 on OpenAlexaff
Lan Qin, Zhenzhen Zhao, Xiangru Kong, Yonggang Li, Chao Yang, Xiao-Bing Deng, Lin-ya Lv, Changchun Li, Shan Wang, Jun Zhang

Bibliographic record

VenueResearch Square · 2024
Typepreprint
Languageen
FieldMedicine
TopicNeuroblastoma Research and Treatments
Canadian institutionsInstitute of Infection and Immunity
Fundersnot available
KeywordsMedicineSurgeryStage (stratigraphy)Invasive surgeryOpen surgeryNeuroblastomaSignificant differenceInternal medicine

Abstract

fetched live from OpenAlex

Abstract Purpose: To explore the feasibility of minimally invasive surgery(MIS)used in the treatment of neuroblastoma. Methods: Selected NB patients were randomly assigned to the MIS group and the open surgery(OS) group. The operative details, major complications, and prognosis of the two groups were compared. Results: A total of 35 children undergoing MIS and 35 children undergoing open surgery were enrolled in this study. According to the INRGSS staging system, 30 patients were classified as stage L1, 32 as stage L2, and 8 as stage M. No statistical difference was found in the age of the children and the maximum diameter of the primary site tumor between the two groups. The bleeding volume in the OS group was significantly higher than that in the MIS group (P=0.006), The time to start postoperative feeding in the MIS group was significantly shorter than that in the OS group (P<0.001). No significant difference was found in the number of GTR between the MIS group and the OS group (P=0.246). The one-year survival rate and overall survival rate of the MIS group were 100% and 93.85%, while the OS group was 100% and 93.72%, respectively. Conclusion: MIS has more advantages than OS for suitable neuroblastoma, while the prognosis is almost the same. After gradually improving the indications for MIS, it should become the preferred surgical method for children within this range.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.150
GPT teacher head0.450
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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