The impact of heterogeneous spatial autocorrelation on comparisons of brain maps
Bibliographic record
Abstract
Abstract It is increasingly common to statistically compare brain maps to assess how spatially similar they are. However, statistical inference can be challenging due to the presence of spatial autocorrelation. Therefore, random permutation approaches based on null models are widely used to address this concern. Here, we show how that the presence of heterogeneity in the spatial autocorrelation across brain maps impacts the validity of statistical inference in common approaches for spatially correlated maps. Furthermore, we illustrate how a Bayesian spatial regression approach can be applied to compare functional and structural cortical brain maps, yielding valid statistical inferences even in the presence of heterogeneity. Explicitly modelling spatial properties provides more valid inferences about whole brain spatial maps allowing a wider and more sophisticated range of neurobiological questions to be answered about the relationship between brain maps than are possible with current approaches.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.049 | 0.243 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.001 | 0.006 |
| Scholarly communication | 0.003 | 0.003 |
| Open science | 0.002 | 0.003 |
| Research integrity | 0.001 | 0.003 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".