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Record W4400014677 · doi:10.1111/cea.14527

The Chronic Angioedema Registry (CARE): Rationale, Methods and Implementation

2024· article· en· W4400014677 on OpenAlexaffabout
Thomas Buttgereit, Felix Aulenbacher, Alexander Gutsche, Pavel Kolkhir, Karsten Weller, Markus Magerl, Henriette Farkas, Anete Sevciovic Grumach, Emel Aygören‐Pürsün, N. Bara, Moshe Ben‐Shoshan, Jonathan A. Bernstein, Stephen Betschel, Laurence Bouillet, Teresa Caballero, Mauro Cancian, Anthony J. Castaldo, Stefan Cimbollek, Danny M. Cohn, T.J. Craig, Daria Fomina, Aslı Gelincik, Vesna Grivcheva‐Panovska, Ankur Kumar Jindal, Constance H. Katelaris, Aharon Kessel, Tamar Kinaciyan, Hilary Longhurst, I. Martinez‐Saguer, Marc A. Riedl, Clemens Schöffl, Petra Staubach, Andrea Zanichelli, Yuxiang Zhi, Jie Shen Fok, Philip H. Li, Roman Hakl, Michihiro Hide, Jonny Peter, Marcus Maurer

Bibliographic record

VenueClinical & Experimental Allergy · 2024
Typearticle
Languageen
FieldMedicine
TopicCoagulation, Bradykinin, Polyphosphates, and Angioedema
Canadian institutionsSt. Michael's HospitalMcGill UniversityUniversity of TorontoMontreal Children's Hospital
FundersKalVista PharmaceuticalsGenentechLEO PharmaEli Lilly and CompanyOno PharmaceuticalCelltrionEisaiIntellia TherapeuticsGrifolsGlaxoSmithKlineConselho Nacional de Desenvolvimento Científico e TecnológicoIpsenGlenmark PharmaceuticalsMitsubishi Tanabe Pharma CorporationBioCrystIonis PharmaceuticalsCelldex TherapeuticsAstraZenecaCSL BehringRegeneron PharmaceuticalsTeva Pharmaceutical IndustriesSanofiTakeda Pharmaceutical CompanyAmgenPfizer
KeywordsMedicineAngioedemaHealth careSpecialtyDisease registryObservational studyDiseaseFamily medicinePathologyInternal medicine

Abstract

fetched live from OpenAlex

712

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.193
metaresearch head score (Gemma)0.168
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.193
Threshold uncertainty score0.995

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1930.168
Meta-epidemiology (narrow)0.0010.002
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0090.009
Science and technology studies0.0030.004
Scholarly communication0.0070.005
Open science0.0060.010
Research integrity0.0030.006
Insufficient payload (model declined to judge)0.0220.010

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.477
Teacher spread0.435 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2024
Admission routes2
Has abstractyes

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