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Record W4400150155 · doi:10.1016/j.cdnut.2024.102223

Adherence to Mediterranean Diet Mediates the Relationship Between Cognition, Sleep, and Daily Autonomy in Mild Cognitive Impairment

2024· article· en· W4400150155 on OpenAlexaboutno aff
Simone Varrasi, Vittoria Torre, Giuseppe Alessio Platania, Claudia Savia Guerrera, Francesco Maria Boccaccio, Concetta Pirrone, Fabio Galvano, Sabrina Castellano

Bibliographic record

VenueCurrent Developments in Nutrition · 2024
Typearticle
Languageen
FieldMedicine
TopicNutritional Studies and Diet
Canadian institutionsnot available
Fundersnot available
KeywordsMediterranean dietCognitionCognitive impairmentAutonomySleep (system call)GerontologyPsychologyMedicineInternal medicinePsychiatryPolitical scienceComputer science

Abstract

fetched live from OpenAlex

Objectives: Adherence to Mediterranean Diet seems to be involved in older adults' health. However, its specific role towards cognitive deficits, daily autonomy, and sleep quality still needs to be clarified. Therefore, this pilot study aimed at: 1) exploring the relationships between adherence to Mediterranean Diet, cognitive decline, daily autonomy, and sleep quality in older adults with Mild Cognitive Impairment (MCI), and 2) computing models to explore the interplay between these variables. Methods: After ethical approval, 12 older adults with MCI (Mini Mental State Examination ≥ 26 and < 28, M = 26.8, SD = 1.82) aged 65+ years (M = 75.7, SD = 7.39) were assessed with Medi-Lite questionnaire on adherence to Mediterranean Diet, Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Frontal Assessment Battery (FAB), Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), and Pittsburgh Sleep Quality Index (PSQI). Data were analyzed with SPSS 27. Results: Adherence to Mediterranean Diet correlated with MMSE attention and calculation (ρ = 0.63, p < .05), MMSE orientation (ρ = 0.58, p < .05), MMSE general cognitive functioning (ρ = 0.67, p < .05), MoCA visuospatial/executive ability (ρ = 0.79, p < .01), MoCA delayed recall (ρ = 0.6, p < .05), FAB conflicting instructions (ρ = 0.61, p < .05), FAB go – no go (ρ = 0.67 p < .05), IADL (ρ = 0.79, p < .05), and PSQI sleep duration (ρ = 0.74, p < .01). PSQI sleep duration, moreover, correlated with FAB go – no go (ρ = 0.67, p < .05), while PSQI subjective quality of sleep correlated with ADL (ρ = -0.7, p < .05). Bootstrap mediation analysis, in conclusion, showed adherence to Mediterranean Diet as a complete mediator in the relationship between MMSE general cognitive functioning and IADL (ab = 0.5, 95% CI [0.13, 1.08], p < .05; c = 0.48, 95% CI [-0.04, 1.25], p = .12; c + ab = 0.98, 95% CI [0.55, 1.86], p < .01), and in the relationship between PSQI sleep duration and IADL (ab = 1.71, 95% CI [0.64, 3.48], p < .05; c = -0.1, 95% CI [-1.89, 1.54]; p = .89; c + ab = 1.61, 95% CI [0.33, 3]; p < .05). Conclusions: Adherence to Mediterranean Diet seems to play an important role in the relationships between cognition, sleep, and daily autonomy in MCI. Future works should be conducted on larger samples to design specific intervention strategies for healthy aging. Funding Sources: None.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.024
Threshold uncertainty score0.632

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.094
GPT teacher head0.358
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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