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Record W4400219672 · doi:10.21203/rs.3.rs-4578348/v1

Using Generative and Explainable Neural Networks to Investigate the Relationship Between Motor Cortex Activity and Animal Behavior During Motor Task Learning.

2024· preprint· en· W4400219672 on OpenAlexafffund
Artur Luczak, Sean Tanabe, Michael J. Eckert, Ian Q. Whishaw, Masami Tatsuno

Bibliographic record

VenueResearch Square · 2024
Typepreprint
Languageen
FieldComputer Science
TopicExplainable Artificial Intelligence (XAI)
Canadian institutionsUniversity of Lethbridge
FundersNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health Research
KeywordsTask (project management)Premovement neuronal activityNeuroscienceComputer scienceGenerative grammarMotor learningPredictabilityMotor cortexAnimal behaviorRelation (database)Artificial intelligenceMotor activityMotor behaviorNeural activityMachine learningPsychologyBiologyEngineering

Abstract

fetched live from OpenAlex

<title>Abstract</title> Understanding complex relations between neuronal activity and animal behavior is one of the most crucial questions in neuroscience. Rapid advancements in Machine Learning (ML) methods offer new powerful tools that can be used to investigate highly non-linear mapping between motor cortex activity and body movements. Here, by using explainable convolutional network (ConvNet) and Generative Adversarial Networks (GAN), we show how neuronal activity can be predicted from raw videos of animal behavior, and interestingly, we show that detailed videos of behaving animals can be recreated from activity of just few selected neurons. Those analyses revealed that the predictability of behavior from neuronal activity (and vice versa) initially increases as an animal learns a new task. However, after the animal performance on a motor task achieves the required accuracy, then “coupling” between neuronal activity and behavior decreases, without degrading task performance. In summary, we show how new ML methods could be applied to provide new insights in the relation between neuronal activity and behavior.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Scholarly communication, Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.479
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0020.000
Scholarly communication0.0020.001
Open science0.0010.007
Research integrity0.0000.004
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.195
GPT teacher head0.413
Teacher spread0.218 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes2
Has abstractyes

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