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Record W4400477483 · doi:10.1016/j.cjcpc.2024.06.002

Assessing Cardiovascular Health in Paediatric Hypertrophic Cardiomyopathy Using the CANHEART Health Index

2024· article· en· W4400477483 on OpenAlexafffundabout
Victoria Srbely, Aamir Jeewa, Tara Pidborochynski, Samuel Lemaire‐Paquette, Michael Khoury, Chentel Cunningham, Santokh Dhillon, Nassiba Alami Laroussi, Laurence Vaujois, Frédéric Dallaire, Daryl Schantz, Kathryn Armstrong, Wadi Mawad, Timothy J. Bradley, Jennifer Conway

Bibliographic record

VenueCJC Pediatric and Congenital Heart Disease · 2024
Typearticle
Languageen
FieldMedicine
TopicCardiomyopathy and Myosin Studies
Canadian institutionsBritish Columbia Children's HospitalCentre Hospitalier Universitaire de SherbrookeUniversité de SherbrookeUniversité de MontréalUniversity of AlbertaMontreal Children's HospitalCentre hospitalier universitaire de QuébecIzaak Walton Killam Health CentreChildren's Hospital of WinnipegStollery Children's HospitalHospital for Sick Children
FundersWomen and Children's Health Research InstituteChildren's Cardiomyopathy FoundationChildren's Health Research Institute
KeywordsHypertrophic cardiomyopathyMedicineIndex (typography)CardiologyInternal medicineCardiovascular healthCardiomyopathyDiseaseHeart failureComputer science

Abstract

fetched live from OpenAlex

BackgroundPaediatric hypertrophic cardiomyopathy (HCM) is associated with sudden cardiac death, often resulting in restriction of strenuous physical activity. High levels of inactivity and a rise in youth obesity may increase risk of poor cardiovascular (CV) health in these patients. We aim to compare the CV disease risk profile of paediatric patients with HCM to Canadian youth.MethodsPatients with HCM (10-19 years) were recruited from 10 paediatric cardiac centres in Canada. The CV disease risk profile was determined using the Healthy Hearts School Program questionnaire and Cardiovascular Health in Ambulatory Care Research Team (CANHEART) health index. Poisson regressions were used to assess associations between the CV disease risk profile of paediatric patients with HCM and the overall CANHEART health score.ResultsA total of 56 subjects were enrolled (71% male, median age: 15.5 years [interquartile range: 13.8-16.8], median body mass index: 23.3 [interquartile range: 19.5-27.7]). Results of the CANHEART health index revealed that 89% of participants with HCM never tried smoking, 52% had a healthy body mass index, 39% consumed ≥5 fruits/vegetables per day, and 50% engaged in ≥60 minutes of walking or 20 minutes of running/jogging per day. When CANHEART intermediate and poor health index scores were combined, similar proportions were obtained for each group (HCM 82.1% vs Canadian youth 83.4%; P = 0.724).ConclusionsMany paediatric patients with HCM in Canada have intermediate or poor CV health as determined by the CANHEART health score, with high rates of obesity and low physical activity levels driving these trends. Interventions should be developed to promote positive CV health behaviours among patients with HCM.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.399
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.304
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2024
Admission routes3
Has abstractyes

Explore more

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