Evaluation of efficacy and safety of Collashot C2 plus capsule in osteoarthritis patients
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Background: Osteoarthritis (OA), the most prevalent joint disease, is marked by chronic joint pain and debilitating symptoms. Many drugs are available in the market for treating osteo arthritis symptoms but there is still need for drugs with least adverse effects. So, in this study, an attempt has been done with Collashot C2 plus capsule, a nutraceutical for treating OA symptoms. Methods: This is an outcome, quasi-experimental study where patients with OA were included. Patients were given capsule Collashot C2 plus daily for 3 months. A total of 30 male and female patients were included in the study. Changes from baseline to 12 weeks in knee pain intensity measured by pain visual analogue scale (VAS) and in Western Ontario and McMaster universities OA index (WOMAC) pain subscale, laboratory parameters, participant's global assessment of improvement of OA were assessed. Adverse drug reactions were also observed during the study period. Results: There was a statistically significant improvement in the VAS pain scale, WOMAC pain score and in participant's global assessment of improvement of OA at week 4, week 8, and week 12 compared to baseline (p<0.001) was observed. Conclusions: Collashot C2 plus capsule has proved to be very safe and effective in the management of OA Participants by reducing inflammation, providing adequate pain relief without causing any major side effects.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.006 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it