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Record W4400701506 · doi:10.1002/adhm.202402215

Surface‐Grafted Biocompatible Polymer Conductors for Stable and Compliant Electrodes for Brain Interfaces

2024· article· en· W4400701506 on OpenAlexfundno aff
Rachel Blau, Samantha M. Russman, Yi Qie, Wade Shipley, Allison Lim, Alexander X. Chen, Audithya Nyayachavadi, Louis Ah, Abdulhameed Abdal, Guillermo L. Esparza, Samuel J. Edmunds, Ritwik Vatsyayan, Sean P. Dunfield, Moumita Halder, Jesse V. Jokerst, David P. Fenning, Andrea R. Tao, Shadi A. Dayeh, Darren J. Lipomi

Bibliographic record

VenueAdvanced Healthcare Materials · 2024
Typearticle
Languageen
FieldNeuroscience
TopicNeuroscience and Neural Engineering
Canadian institutionsnot available
FundersAir Force Office of Scientific ResearchDivision of ChemistryNational Institute of Neurological Disorders and StrokeDivision of Chemical, Bioengineering, Environmental, and Transport SystemsBRAIN InitiativeNational Institute of Biomedical Imaging and BioengineeringKuwait Foundation for the Advancement of SciencesAlfred P. Sloan FoundationNatural Sciences and Engineering Research Council of CanadaDivision of Electrical, Communications and Cyber SystemsEuropean CommissionNational Institutes of HealthNational Science FoundationH2020 Marie Skłodowska-Curie ActionsUC Irvine Materials Research Institute
KeywordsMaterials scienceAtom-transfer radical-polymerizationPolymer brushPolymerEthylene glycolCopolymerConductive polymerElectrodeBioelectronicsElectrical conductorBrushMethacrylateAdhesionElectrolyteNanotechnologyChemical engineeringPolymer chemistryPolymerizationComposite materialBiosensorChemistry

Abstract

fetched live from OpenAlex

Abstract Durable and conductive interfaces that enable chronic and high‐resolution recording of neural activity are essential for understanding and treating neurodegenerative disorders. These chronic implants require long‐term stability and small contact areas. Consequently, they are often coated with a blend of conductive polymers and are crosslinked to enhance durability despite the potentially deleterious effect of crosslinking on the mechanical and electrical properties. Here the grafting of the poly(3,4 ethylenedioxythiophene) scaffold, poly(styrenesulfonate)‐ b ‐poly(poly(ethylene glycol) methyl ether methacrylate block copolymer brush to gold, in a controlled and tunable manner, by surface‐initiated atom‐transfer radical polymerization (SI‐ATRP) is described. This “block‐brush” provides high volumetric capacitance (120 F cm ─3 ), strong adhesion to the metal (4 h ultrasonication), improved surface hydrophilicity, and stability against 10 000 charge–discharge voltage sweeps on a multiarray neural electrode. In addition, the block‐brush film showed 33% improved stability against current pulsing. This approach can open numerous avenues for exploring specialized polymer brushes for bioelectronics research and application.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.793

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.071
GPT teacher head0.360
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2024
Admission routes1
Has abstractyes

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