MétaCan
Menu
Back to cohort
Record W4401011803 · doi:10.1038/s41467-024-50601-9

Evaluation of FluSight influenza forecasting in the 2021–22 and 2022–23 seasons with a new target laboratory-confirmed influenza hospitalizations

2024· article· en· W4401011803 on OpenAlexaff
Sarabeth M. Mathis, Alexander E. Webber, Tomás M. León, Erin L. Murray, Monica Sun, Lauren A. White, Logan Brooks, Alden Green, Addison J. Hu, Roni Rosenfeld, Dmitry Shemetov, Ryan J. Tibshirani, Daniel J. McDonald, Sasikiran Kandula, Sen Pei, Rami Yaari, Teresa K. Yamana, Jeffrey Shaman, Pulak Agarwal, Srikar Balusu, Gautham Gururajan, Harshavardhan Kamarthi, B. Aditya Prakash, Rishi Raman, Zhiyuan Zhao, Alexander Rodríguez, Akilan Meiyappan, Shalina Omar, Prasith Baccam, Heidi Gurung, Brad T. Suchoski, Steve A. Stage, Marco Ajelli, Allisandra G. Kummer, Maria Litvinova, Paulo C. Ventura, Spencer Wadsworth, Jarad Niemi, Erica Carcelen, Alison L. Hill, Sara L. Loo, Clifton McKee, K.T. Sato, Claire P. Smith, Shaun Truelove, Sung-mok Jung, Joseph C. Lemaitre, Justin Lessler, Thomas McAndrew, Wenxuan Ye, Nikos I Bosse, William S. Hlavacek, Yen Ting Lin, Abhishek Mallela, Graham Gibson, Ye Chen, Shelby M. Lamm, Jaechoul Lee, Richard G. Posner, Amanda C. Perofsky, Cécile Viboud, Leonardo Clemente, Fred Lu, Austin G. Meyer, Mauricio Santillana, Matteo Chinazzi, Jessica T. Davis, Kunpeng Mu, Ana Pastore y Piontti, Alessandro Vespignani, Xinyue Xiong, M. Ben-Nun, Pete Riley, James Turtle, Chis Hulme-Lowe, Shakeel Jessa, VP Nagraj, Stephen Turner, Desiree Williams, Avranil Basu, John M. Drake, Spencer J. Fox, Ehsan Suez, M Cojocaru, Edward W. Thommes, Estee Y. Cramer, Aaron Gerding, Ariane Stark, Evan L Ray, Nicholas G Reich, Li Shandross, Nutcha Wattanachit, Yijin Wang, Martha Zorn, Majd Al Aawar, Ajitesh Srivastava, Lauren Ancel Meyers, Aniruddha Adiga, Benjamin Hurt, Gursharn Kaur, Bryan Lewis, Madhav Marathe, Srinivasan Venkatramanan, P. J. Butler, Andrew Farabow, Naren Ramakrishnan, Nikhil Muralidhar, Carrie Reed, Matthew Biggerstaff, Rebecca K. Borchering

Bibliographic record

VenueNature Communications · 2024
Typearticle
Languageen
FieldMedicine
TopicInfluenza Virus Research Studies
Canadian institutionsSanofi (Canada)University of GuelphUniversity of British Columbia
FundersLos Alamos National LaboratoryNational Institute of Allergy and Infectious DiseasesNational Institute of General Medical SciencesCenters for Disease Control and PreventionResearch Institute, Georgia Institute of TechnologyVirginia Department of HealthLaboratory Directed Research and DevelopmentCouncil of State and Territorial EpidemiologistsNational Institutes of HealthU.S. Department of Health and Human ServicesNational Science Foundation
KeywordsSeasonal influenzaBaseline (sea)Probabilistic logicConfidence intervalStatisticsPublic healthInterval (graph theory)Forecast skillMedicineEconometricsCoronavirus disease 2019 (COVID-19)Internal medicineMathematicsBiologyInfectious disease (medical specialty)Pathology

Abstract

fetched live from OpenAlex

Abstract Accurate forecasts can enable more effective public health responses during seasonal influenza epidemics. For the 2021–22 and 2022–23 influenza seasons, 26 forecasting teams provided national and jurisdiction-specific probabilistic predictions of weekly confirmed influenza hospital admissions for one-to-four weeks ahead. Forecast skill is evaluated using the Weighted Interval Score (WIS), relative WIS, and coverage. Six out of 23 models outperform the baseline model across forecast weeks and locations in 2021–22 and 12 out of 18 models in 2022–23. Averaging across all forecast targets, the FluSight ensemble is the 2 nd most accurate model measured by WIS in 2021–22 and the 5 th most accurate in the 2022–23 season. Forecast skill and 95% coverage for the FluSight ensemble and most component models degrade over longer forecast horizons. In this work we demonstrate that while the FluSight ensemble was a robust predictor, even ensembles face challenges during periods of rapid change.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.480
Threshold uncertainty score0.567

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.098
GPT teacher head0.415
Teacher spread0.317 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations56
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueNature CommunicationsSame topicInfluenza Virus Research StudiesFrench-language works237,207