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Record W4401687766 · doi:10.1101/2024.08.18.608476

The effect of extended cold storage and the use of extenders on motility and swimming kinematics of shortnose sturgeon sperm

2024· preprint· en· W4401687766 on OpenAlexaffabout
Kenzie H. Melanson, Matthew K. Litvak

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2024
Typepreprint
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicReproductive biology and impacts on aquatic species
Canadian institutionsSaint Mary's UniversityMount Allison University
Fundersnot available
KeywordsSpermKinematicsAcipenserFisheryMotilityCold storageSperm motilitySturgeonBiologyFish <Actinopterygii>Cell biologyPhysicsGenetics

Abstract

fetched live from OpenAlex

ABSTRACT Shortnose sturgeon are listed as a species of special concern in Canada and as endangered in the US. Increasing knowledge about this species, particularly in the area of reproductive biology, will better the management of wild populations and aid in the development of assisted reproduction protocols. However, access to wild sperm is limited, so short-term and long-term storage of sperm from sturgeon is crucial for reproductive studies. Here we report on testing and development of a short-term storage protocol for shortnose sturgeon. Milt samples were collected from wild shortnose sturgeon caught in the Wolastoq River. Subsets of semen were mixed with different extenders with or without oxygen; control treatments without extenders were also run. We used computer-assisted sperm analysis (CASA) to determine sperm motility and swimming kinematics for the different treatments. All groups were examined immediately after collection and treatment application, and then 1, 2, and 7 days after storage in a fridge (4°C) for experiment 1, and days 1, 3, 7, 10, 14, 17, 21, and 24 for experiment 2. The response variables motility, curvilinear velocity (VCL), linearity (LIN), and wobble (WOB) showed an overall decrease over time with differences between extender treatments. While untreated milt maintained some motility up to day 21, the addition of an extender reduced decline in motility and improved longevity up to day 24. Milt treated with the Park and Chapman extender had the slowest motility decline of extenders used, and milt treated with the modified Tsvetkova extender showed less potential for contamination.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.240
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes2
Has abstractyes

Explore more

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