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Oxytocin at Elective Cesarean Delivery: A Dose-finding Study in Pregnant People With Twin Pregnancy

2024· article· en· W4401833486 on OpenAlexaff
Emil Peska, Mrinalini Balki, Wolfgang Pfeifer, Cynthia Maxwell, X. Ye, Kristi Downey, J.C.A. Carvalho

Bibliographic record

VenueObstetric Anesthesia Digest · 2024
Typearticle
Languageen
FieldMedicine
TopicMaternal and fetal healthcare
Canadian institutionsUniversity of TorontoMount Sinai Hospital
Fundersnot available
KeywordsUterine atonyMedicineOxytocinObstetricsPregnancyAtonyHysterectomyPostpartum haemorrhageCesarean deliveryGynecologyAdverse effectSurgeryInternal medicine

Abstract

fetched live from OpenAlex

(Anesth Analg. 2024;138(4):814–820. doi:10.1213/ANE.0000000000006309) Multiple pregnancies pose a well-known danger for postpartum hemorrhage (PPH). Compared with single pregnancies, individuals expecting multiples face heightened risks like uterine atony, severe PPH, blood transfusion, hysterectomy, prolonged hospital stays, and mortality, regardless of income level. Uterine atony, a significant cause of PPH, is more common in multiple pregnancies. Prophylactic oxytocin postdelivery is crucial in PPH prevention, though it can have adverse effects and should be given at the minimum effective dose. Studies suggest varying oxytocin requirements based on clinical scenarios like body mass index and cesarean delivery (CD) for labor complications in multiple pregnancies, prompting the need for tailored dosages for PPH prevention.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.277
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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