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Record W4401988558 · doi:10.1371/journal.pone.0307999

Accumulating evidence across studies: Consistent methods protect against false findings produced by p-hacking

2024· article· en· W4401988558 on OpenAlexaff
Duane T. Wegener, Jolynn Pek, Leandre R. Fabrigar

Bibliographic record

VenuePLoS ONE · 2024
Typearticle
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsQueen's University
Fundersnot available
KeywordsHackerBiologyBioinformaticsMedicineComputational biologyComputer scienceComputer security

Abstract

fetched live from OpenAlex

Much empirical science involves evaluating alternative explanations for the obtained data. For example, given certain assumptions underlying a statistical test, a "significant" result generally refers to implausibility of a null (zero) effect in the population producing the obtained study data. However, methodological work on various versions of p-hacking (i.e., using different analysis strategies until a "significant" result is produced) questions whether significant p-values might often reflect false findings. Indeed, initial simulations of single studies showed that the potential for finding "significant" but false findings might be much higher than the nominal .05 value when various analysis flexibilities are undertaken. In many settings, however, research articles report multiple studies using consistent methods across the studies, where those consistent methods would constrain the flexibilities used to produce high false-finding rates for simulations of single studies. Thus, we conducted simulations of study sets. These simulations show that consistent methods across studies (i.e., consistent in terms of which measures are analyzed, which conditions are included, and whether and how covariates are included) dramatically reduce the potential for flexible research practices (p-hacking) to produce consistent sets of significant results across studies. For p-hacking to produce even modest probabilities of a consistent set of studies would require (a) a large amount of selectivity in study reporting and (b) severe (and quite intentional) versions of p-hacking. With no more than modest selective reporting and with consistent methods across studies, p-hacking does not provide a plausible explanation for consistent empirical results across studies, especially as the size of the reported study set increases. In addition, the simulations show that p-hacking can produce high rates of false findings for single studies with very large samples. In contrast, a series of methodologically-consistent studies (even with much smaller samples) is much less vulnerable to the forms of p-hacking examined in the simulations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.694
metaresearch head score (Gemma)0.903
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: Methods
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.306
Threshold uncertainty score0.378

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.6940.903
Meta-epidemiology (narrow)0.0050.005
Meta-epidemiology (broad)0.0100.015
Bibliometrics0.0140.012
Science and technology studies0.0050.027
Scholarly communication0.0140.016
Open science0.0120.019
Research integrity0.0160.021
Insufficient payload (model declined to judge)0.0110.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.945
GPT teacher head0.646
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designSimulation or modeling
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2024
Admission routes1
Has abstractyes

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