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Abstract B069: ACCESS: Advancing childhood cancer experience, science and survivorship in Canada

2024· article· en· W4402266851 on OpenAlexaffabout
Stephanie A. Grover, Christine Williams, Adrienne Co-Dyre, David Malkin, James A. Whitlock

Bibliographic record

VenueCancer Research · 2024
Typearticle
Languageen
FieldMedicine
TopicChildhood Cancer Survivors' Quality of Life
Canadian institutionsThe King's UniversityWestern UniversityOntario Institute for Cancer ResearchHospital for Sick Children
Fundersnot available
KeywordsSurvivorship curveChildhood cancerCancerCancer survivorshipMedicineGerontologyInternal medicine

Abstract

fetched live from OpenAlex

Abstract In Canada, roughly 1,500 children and adolescents are diagnosed with cancer each year. Advocacy for enhanced childhood cancer research and care in Canada by patients, families and the academic community led to a $23M investment through the Canadian Institutes of Health Research to establish a national pediatric cancer consortium (termed ‘ACCESS’). ACCESS’ mission is to ensure every child with cancer in Canada has access to the latest scientific advances, diagnostic tools, therapies, and supportive care leading to better outcomes and quality of life. ACCESS is a unique collective of scientists, healthcare providers, industry leaders, partner organizations, advocates, patients, and their families who are conducting research, changing policy, and developing new tools to ensure better lives for children who experience cancer in Canada and for their loved ones. The goal is to implement transformative change in the delivery of fair, fast, effective, and safe cancer care for all children. ACCESS is driven and led by people with lived experience of pediatric cancer and framed by the patient journey. In its first year, ACCESS has unified a national community. It has: connected a community of more than 700 people and stimulated a culture of open communication in which diverse viewpoints, including those of people with lived experience of cancer, are sought and valued; built productive and effective partnerships to connect and leverage the work of organizations working to improve childhood cancer; initiated 20 new innovative pan-Canadian research studies that impact all aspects of the patient journey, including new Canadian-led clinical trials; developed an educational hub for all ACCESS members, and produced accessible communications materials such as webinars, a newsletter and a comprehensive website; developed national best practice standards and tools for research and care; started to address the complex policy, regulatory and practical barriers that prevent equitable access to cancer diagnosis and treatment for all children in Canada.Future priorities include development of a national data system for pediatric cancer, modernizing pediatric clinical trials to reduce barriers to participation in Canada, and the development of a national strategy for pediatric cancer. Citation Format: Stephanie A. Grover, Christine J. Williams, Adrienne Co-Dyre, David Malkin, James A. Whitlock, on behalf of the ACCESS consortium. ACCESS: Advancing childhood cancer experience, science and survivorship in Canada [abstract]. In: Proceedings of the AACR Special Conference in Cancer Research: Advances in Pediatric Cancer Research; 2024 Sep 5-8; Toronto, Ontario, Canada. Philadelphia (PA): AACR; Cancer Res 2024;84(17 Suppl):Abstract nr B069.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.894
Threshold uncertainty score0.768

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.004
Science and technology studies0.0130.003
Scholarly communication0.0050.002
Open science0.0010.005
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0090.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.103
GPT teacher head0.465
Teacher spread0.362 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes2
Has abstractyes

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