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Record W4402359226 · doi:10.1002/uog.28330

EP08.02: Growth follow‐up on fetuses with single umbilical artery or persistent right umbilical vein: is a 28–32‐week ultrasound needed?

2024· article· en· W4402359226 on OpenAlexaffabout
Sandra Fitzpatrick, Mayura Kale, David Somerset, Nancy Soliman

Bibliographic record

VenueUltrasound in Obstetrics and Gynecology · 2024
Typearticle
Languageen
FieldMedicine
TopicPregnancy and preeclampsia studies
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsUmbilical veinMedicineUmbilical arteryUltrasoundSingle umbilical arteryFetusCardiologyRadiologyPregnancyBiology

Abstract

fetched live from OpenAlex

Pregnancies found to have a single umbilical artery (SUA) or persistent right umbilical vein (PRUV) are associated with fetal anomalies. If targeted ultrasound and screening fetal ECHO finds otherwise normal anatomy, there is an increased risk of small for gestational age (SGA). The purpose of this study is to determine if current practice of recommending growth assessments between 28-32 detects (SGA) fetuses in this population. We conducted a retrospective review of 753 singleton pregnancies with SUA, and 44 with PRUV between January 2017- 2020, through the Calgary MFM Center. 466 SUA and 36 PRUV pregnancies were analysed. Pregnancies that were terminated due to anomalies, or those missing delivery/ultrasound surveillance data were excluded. The primary outcome was the rate of SGA fetuses. Secondary outcome was the detection rate of SGA at current recommended follow up ultrasound protocol. We found 19.1% (n = 89, 95% CI 15.6% to 22.7%) of all SUA pregnancies and 5.6% (n = 2, 95% CI 0.7% to 19.2) of PRUV pregnancies were SGA at time of delivery (baseline rate of SGA from unpublished local Calgary data of low risk pregnancies is 12%). Of SUA pregnancies that were SGA at delivery, 67.4% did not have SGA noted on ultrasound throughout the pregnancy, and SGA was first noted at time of delivery. Only 2.8% (95% CI 1.4% to 4.6%) of SUA pregnancies and 0% (95% CI 0.0% to 10.0%) of PRUV pregnancies were found to be SGA at 28-32wk ultrasound (the current local protocol for growth follow up of SUA and PRUV pregnancies). SUA and PRUV have known increased risk of SGA, our data shows that SUA confers a larger risk for SGA than PRUV. However, in analysis of ultrasound data from our centre, routine ultrasound at 28-32wk did not increase the detection of SGA in these pregnancies. We recommend that if there is no concern for SGA at the time of detailed ultrasound or fetal ECHO, then a 28-32wk ultrasound is not necessary and one ultrasound in the later third trimester is sufficient for monitoring in the absence of other clinical concerns.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.018
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.027

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.018
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.255
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes2
Has abstractyes

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