From individual motivation to substance use initiation: A longitudinal cohort study assessing the associations between reward sensitivity and subsequent risk of substance use initiation among US adolescents
Bibliographic record
Abstract
BACKGROUND: Substance use in youth remains a pressing problem in the United States. Existing studies have shown the importance of neuropathways responsible for affective response and reward motivation in adolescents' substance use initiation and maintenance. However, limited observational studies have explored the relationship between aspects of behavioral motivation traits and the likelihood of substance use initiation in adolescents. In this prospective cohort study, we assessed the associations between behavioral motivation traits based on the Behavioral Inhibition and Approach Systems (BIS-BAS) Scale and substance use initiation using data from the Adolescent Brain Cognitive Development (ABCD) study. METHOD: In the 9216 eligible sample population, we assessed the associations between mean Behavioral Inhibition System (BIS) / Behavioral Approach System (BAS) scores measured at year 2 of the ABCD study and substance use initiation at year 3 of the ABCD study using multivariable logistic regressions adjusting for ABCD study site, sampling weights, as well as sociodemographic characteristics. RESULTS: We found that higher BIS mean score was associated with higher odds of initiating substance use at year 3 (AOR=1.20, 95 % CI: 1.03, 1.40). Out of three BAS measure categories, only BAS Fun-seeking mean score was positively associated with higher odds of initiating substance use at year 3 (AOR=1.23, 95 % CI: 1.07, 1.43). CONCLUSION: Our study showed that inhibitory and fun-seeking behavioral tendencies are associated with an increased likelihood of substance use initiation in adolescents. Our findings suggest a potential pathway linking emotional traits to early substance initiation in adolescents.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.002 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".