Proceedings of the 2024 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Annual Scientific Meeting
Bibliographic record
Abstract
NSAIDshort (n=32) NSAIDlong (n=62) Secondline (n=70) P value Overall (n=164) Mean number out of 6 regions affected ( SD) 1.22 ( 0.608) 1.31 ( 0.561) 2.06 ( 1.03) <0.001 1.61 ( 0.890) Symmetric involvement in the same bone, n (%) 5 (16%) 14 (23%) 51 (73%) <0.001 70 (43%) Mean days on NSAID monotherapy, days ( SD) 175 ( 26.5) 725 (512) 441 (536) <0.001 497 (511) Number of NSAIDs Trialed, n (%) <0.001 0 0 (0%) 0 (0%) 2 (3%) 2 (1%) 1 30 (94%) 28 (45%) 17 (24%) 75 (46%) 2 2 (6%) 32 (52%) 45 (64%) 79 (48%) 3 or more 0 (0%) 3 (3%) 6 (9%) 8 (5%) Patients with complications, n (%) Vertebral height loss 0 (0%) 8 (13%) 14 (20%) 0.0215 22 (13%) Amplified pain 0 (0%) 3 (5%) 10 (14%) 0.02 13 (8%) Patients in each disease activity state at study end date, n (%) Active disease 0 (0%) 7 (11%) 14 (20%) 0.024 21 (13%) Inactive disease on treatment 2 (6%) 11 (18%) 20 (29%) 0.0285 33 (20%) Remission 30 (94%) 44 (71%) 36 (51%) <0.001 110 (67%)Table 2 (Abstract A1) Linear regression modeling with AIC-based variable selection comparing the NSAID-short and NSAID-long groups Study Variable Coefficient P-value Unifocal disease at diagnosis -0.386 0.029 Number of regions affected -0.225 0.141 Onset to treatment interval 0.000 0.162 On average, patients with unifocal disease at diagnosis require 47.11% less days of total NSAID monotherapy treatment than patients with multifocal disease at diagnosis.P-values here correspond to a one-way ANOVA for numeric variables and chi-squared test for categorical variables A3 Tubulointerstitial inflammation is associated with end-stage renal disease in pediatric lupus nephritis,
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".