482 Using growth implants in suckling beef calves enhanced vaccine response against Infectious Bovine Rhinotracheitis
Bibliographic record
Abstract
Abstract This study aimed to evaluate vaccine response, growth performance, and immunity of beef calves under different implant strategies. Crossbreed beef calves [n = 90; 39 ± 2.3 kg of body weight (BW) and 80 d of age] were stratified by birth BW and age and were randomly assigned (30 per treatment) to 1 of 3 treatments in a randomized complete block design: 1) implanted with 100 mg progesterone and 10 mg estradiol benzoate (Synovex C, SC, Zoetis Inc.), 2) implanted with 150 mg trenbolone acetate and 21 mg estradiol benzoate (Synovex One Grower, SG, Zoetis Inc.), or 3) no implant (CON). After treatment allocation (d 0) and until weaning (d 151 ± 13.4), all calves were raised alongside their dams and received the same vaccine protocol (Bovi-Shield Gold One Shot and Ultrabac 7) on d 0 and at weaning. Following weaning, calves were allocated to a single pen and received ad libitum total mixed ration until d 60 post-weaning. Body weight and blood samples were collected on d 0, 14, weaning, and on d 14 and 60 post-weaning. Plasma was analyzed for insulin-like growth factor (IGF-1), cortisol, and β-hydroxybutyric acid (BHBA), while serum and whole blood samples were analyzed for serum antibody titers and complete blood count, respectively. Activity budget was recorded for 5 d following weaning with an accelerometer device. A treatment effect (P = 0.01) was detected for serum infectious bovine rhinotracheitis titers, with serum titers being greater in SG than in CON and SC. The SC calves had greater IGF-1 (P = 0.03) compared with CON but not with SG. There was a treatment × day interaction (P = 0.01) for leukocytes where SC was greater than CON but not than SG on the weaning day. Haptoglobin was less (P = 0.02) in SG calves compared with SC and CON. A treatment × day interaction was detected for BHBA (P = 0.04), with SC having decreased concentrations on d 14 post-vaccines compared with SG and CON, while CON was less than SG but not than SC at weaning. Hematocrits were less in SG (P = 0.03) than in SC and CON. There were no differences (P > 0.05) in step count, lying and standing time. Average daily gain (ADG) from d 0 to weaning was greater (P < 0.01) in SG calves compared with CON, but not SC, and ADG from weaning to d 60 post-weaning was greater (P = 0.03) for both SC and SG compared with CON. Weaning weight was greater in SC and SG calves (P ≤ 0.01) and on d 14 and 60 post-weaning compared with CON. In summary, implanting suckling beef calves enhanced immune response and improved growth performance before and after weaning.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".