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Record W4402533459 · doi:10.1093/jas/skae234.037

114 Accuracy of genomic predictions using single and multiple-trait machine learning methods in Canadian beef cattle population

2024· article· en· W4402533459 on OpenAlexaffabout
Hongwei Li, Yining Wang, Michael Vinsky, Tiago S. Valente, J. A. Basarab, Changxi Li

Bibliographic record

VenueJournal of Animal Science · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and phenotypic traits in livestock
Canadian institutionsAgriculture and Agri-Food CanadaUniversity of Alberta
Fundersnot available
KeywordsBeef cattleTraitGenomic selectionPopulationBiologyStatisticsAnimal scienceBiotechnologyMathematicsComputer scienceGeneticsGenotypeSingle-nucleotide polymorphismMedicineGeneEnvironmental health

Abstract

fetched live from OpenAlex

Abstract The advancement in various machine learning (ML) methods provides tools to extract features from a large data set of complex traits and to predict the outcome of the target trait. In this study, we assessed the genomic prediction accuracy using single trait models based on kernel ridge regression (ST_KRR) and linear support vector regression (STLinearSVR) for female feed intake, feed efficiency and fertility traits of Canadian crossbreed beef cattle (n = 2,834 genotyped with 83,875 single nucleotide polymorphisms) and compared their prediction performances to a single trait genomic best linear unbiased prediction (STGBLUP) method. We also evaluated the performances of multiple-trait genomic prediction methods including MAK-based KRR, MAK-based LinearSVR (MAK_MTLinearSVR), and multiple-trait genomic best linear unbiased prediction (MTGBLUP). For the single trait methods, we found that the ST_KRR model was 1.86% to 26.86% more accurate for feed intake and fertility traits including residual feed intake adjusted for backfat thickness (RFIfat), daily dry matter intake (DMI), feeding event duration (DUR), age of first calving (AFC), pre-breeding backfat at first parity (PBBF), and pre-breeding weight at first parity (PBWT) than the STGBLUP method, which had an average accuracy of 0.39 for the traits investigated. For growth and development traits including julian date of birth (JulianDt), weaning weight adjusted to 200 d (WT200d), and birth weight (BRWT) of heifers, STLinearSVR yielded a 5.44% to 9.92% greater accuracy than STGBLUP. As for the multiple trait methods, MAK_MTLinearSVR had a 1.1% to 20.42% greater accuracy for PBWT, AFC, WT200d, DUR, RFIfat, and BRWT than the single trait model of STLinearSVR, while MTGBLUP had a 0.42% to 32.64% greater accuracy for AFC, RFIfat, WT200d and PBBF than the single trait model of STGBLUP. Our results demonstrate the potential application of ML-based multiple-trait models in beef cattle to improve the effectiveness of genomic selection programs, in particular for traits with low heritability.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.493
Threshold uncertainty score0.992

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.008
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.330
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes2
Has abstractyes

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