MétaCan
Menu
Back to cohort
Record W4402666118 · doi:10.1016/j.rmcr.2024.102110

Psyllium husk (Metamucil®) induced perennial asthma: A case report

2024· article· en· W4402666118 on OpenAlexaff
Arshdeep Marwaha, Donald W. Cockcroft, Brianne Philipenko

Bibliographic record

VenueRespiratory Medicine Case Reports · 2024
Typearticle
Languageen
FieldMedicine
TopicOccupational exposure and asthma
Canadian institutionsUniversity of Saskatchewan
Fundersnot available
KeywordsMedicineHuskAsthmaPsylliumPerennial plantDermatologyFood scienceInternal medicineAgronomyBotanyDietary fiber

Abstract

fetched live from OpenAlex

Metamucil®, a soluble fiber supplement for constipation, triggered new onset asthma symptoms in a 44-year-old sensitised nurse after a single inhaled exposure. After the initial event, she had no further exposures. She continued to face challenges with exacerbations, poor asthma control, and chronic cough. Despite 30 years of clinic follow-up, her asthma remained difficult to manage, requiring chronic prednisone. While tapering off corticosteroids, she developed polymyalgia rheumatica. This case underscores that psyllium in Metamucil® can cause reactions ranging from mild to severe, even with a single inhaled exposure, emphasising the need for caution in those without a history of asthma. • Psyllium, commonly used in food products and laxatives, can cause severe allergic reactions, including respiratory distress and anaphylaxis, particularly in healthcare and pharmaceutical workers. • A case study of a nurse revealed that even a single exposure to psyllium can lead to long-term, difficult-to-manage asthma. • To mitigate risks, workplaces should maintain high cleanliness standards, properly handle psyllium, and use granulated forms to reduce inhalation hazards.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0030.002
Science and technology studies0.0030.002
Scholarly communication0.0030.003
Open science0.0010.002
Research integrity0.0080.005
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.049
GPT teacher head0.353
Teacher spread0.304 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueRespiratory Medicine Case ReportsSame topicOccupational exposure and asthmaFrench-language works237,207