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Record W4402845661 · doi:10.5327/1516-3180.140s1.7301

DETERMINAÇÃO DE INTERVALOS DE REFERÊNCIAS DE BIOMARCADORES DA FUNÇÃO RENAL EM PACIENTES IDOSOS

2022· article· pt· W4402845661 on OpenAlexaboutno aff
GO Gonçalves, LS Vasconcellos

Bibliographic record

Venuenot available
Typearticle
Languagept
FieldSocial Sciences
TopicPublic Health in Brazil
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineComputer science

Abstract

fetched live from OpenAlex

Objetivo: Sabendo que alterações fisiológicas são esperadas com o avançar da idade, cabe aos laboratórios se adaptarem, principalmente em relação à determinação de intervalos de referência que atendam essa realidade. O objetivo principal deste trabalho é determinar os intervalos de referências (IR) para ureia e creatinina em pacientes idosos. Método: Trata-se de um estudo descritivo transversal que utilizou resultados dos exames laboratoriais de pacientes idosos (> 60 anos) saudáveis (classificados como de baixo ou moderado risco de vulnerabilidade clínico funcional) atendidos em um ambulatório de geriatria, entre os anos de 2011 e 2019. Para determinar os IR, aplicaram-se critérios de inclusão e exclusão conforme o biomarcador avaliado, seguindo os parâmetros da literatura. As análises foram realizadas no software GraphPad Prism®, considerando intervalo de confiança (IC) de 95%. Conclusão: Participaram do estudo 2.292 idosos, cuja média de idade foi de 77 anos. Os resultados de IR para creatinina e ureia em pacientes de ambos os gêneros estão descritos na Tabela a seguir.A determinação dos IR de acordo com a idade, o gênero e a região é indispensável para a aplicação de uma prática clínica segura. Os IR foram semelhantes a outros trabalhos da literatura e podem auxiliar a interpretação das análises laboratoriais e o acompanhamento clínico mais adequados do idoso. Referências: 1. Adeli K et al. Biochemical marker reference values across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the basis of the Canadian Health Measures Survey. Clin Chem. 2015; 61(8): 1049-62.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.029
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.051

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.029
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.003
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.089
GPT teacher head0.391
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2022
Admission routes1
Has abstractyes

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