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Record W4402956183 · doi:10.5376/bm.2024.15.0018

Effects of Exposure to Sublethal Concentrations of Hexavalent Chromium on the Redox Homeostasis of Periwinkle (Tympanotonos fuscatus Linnaeus)

2024· article· en· W4402956183 on OpenAlexvenueno aff
Olufemi Samson Salami, Olufemi S. Bamidele, Chris O. Adedire, Joseph A. Adeyemi

Bibliographic record

VenueBioscience Methods · 2024
Typearticle
Languageen
FieldEnvironmental Science
TopicMercury impact and mitigation studies
Canadian institutionsnot available
Fundersnot available
KeywordsHexavalent chromiumBiologyRedoxHomeostasisChromiumCell biologyChemistryInorganic chemistry

Abstract

fetched live from OpenAlex

The imbalance between the rate of production of reactive oxygen species (ROS) and the ability of the body to scavenge harmful free radicals (ROS) results in oxidative stress. Hexavalent chromium (Cr 6+ ) is a toxic oxidation state of chromium that induces oxidative stress at high concentrations. In this study, periwinkles were exposed to sublethal concentrations (0.42, 0.84, and 4.2 mgl -1 ) of Cr 6+  for 30 days while the unexposed animals served as control (0 mgl -1 ). Thereafter, the activities of superoxide dismutase, catalase, and glutathione peroxidase, and the levels of reduced glutathione as well as lipid peroxidation were determined using standard procedures. The results show that there was a concentration-dependent significant increase in the activities of superoxide dismutase, catalase and glutathione peroxidase in the exposed animals compared to the control. The levels of reduced glutathione and lipid peroxidation decreased significantly in the exposed animals compared to the control. The results indicate that exposure to sublethal concentrations of Cr 6+  can modulate redox homeostasis of periwinkles and consequently result in oxidative stress. The stress pattern shown by periwinkles in the presence of chemical stressor, Cr 6+  can be an indicator for chemical pollutant in the environment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.341
Teacher spread0.314 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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