Efficacy of Dorsal Root Ganglion Stimulation for Chronic Pain in Leprosy: A Case Report
Bibliographic record
Abstract
BACKGROUND: Leprosy is a chronic infectious disease that can be associated with refractory neuropathic pain. Neuromodulation with dorsal root ganglion stimulation (DRGS) represents a novel potential therapeutic option for the nonpharmacological management of leprosy-associated chronic pain. CASE REPORT: We present a case of a leprosy-associated chronic lower extremity neuropathic pain in a 56-year-old man managed with DRGS. The patient underwent implantation of DRG electrodes at the left L5 and right S1 levels for refractory lower extremity pain. Following the procedure, reported significant reduction in pain intensity, decreased analgesic requirements, and improved functionality at short-term follow-up, with no reported postprocedure complications. CONCLUSIONS: The successful treatment of post-leprosy neuropathic pain with DRGS contributes to the expanding body of evidence supporting the use of neuromodulation in the management of treatment-refractory pain. We suggest that DRGS may be a viable interventional option for chronic neuropathic pain from leprosy and other potential indications. KEY WORDS: Dorsal root ganglion stimulation, neuromodulation, chronic pain, leprosy, case report
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.013 | 0.014 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".