Preventive Action of Blue Lotus (Nymphaea Caerulea) Flower Extract against E. Coli-Induced Immune-Pathological Changes In Gallus gallus domesticus Embryo.
Why this work is in the frame
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Bibliographic record
Abstract
Nymphaea caerulea is an aquatic plant originally found in the Nile River has several therapeutic activities - anti-depressant, anti-inflammatory, anti-oxidant, and anti-microbial activities. This led us to perform the study focusing on the anti-microbial properties of the flower extract. Crude ethanolic extract of petals and pollens of N. caerulea flower were prepared and its antimicrobial activity was checked against E. coli. The Minimum Inhibition Concentration value was determined showing that both the extracts had similar capability against both the strains, with MIC value of 0.39mg/ml and 0.78mg/ml MIC against E.coli ATCC and MDR strains respectively. Further studies were done to study the gross morphological changes and the genetic expression changes of IL-10 and IFN-γ in E. coli-infected Gallus gallus domesticus embryo models. From the results, it can be said that the extract has preventive effects that reduce haemorrhages of the embryos when infected with E. coli. Moreover, there was slight increase in the level of IL-10 cytokine gene expression indicating its anti-inflammatory action along with a higher increase in the IFN-γ cytokine gene expressions responsible for activating the host immunity. Thus, the findings indicate the probable potential role of N. caerulea flower extract to act as an antibacterial agent.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it