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Record W4403085136 · doi:10.20956/ijab.v7i2.31831

Preventive Action of Blue Lotus (Nymphaea Caerulea) Flower Extract against E. Coli-Induced Immune-Pathological Changes In Gallus gallus domesticus Embryo.

2023· article· en· W4403085136 on OpenAlexaff
Satadal Das, Subhanjana Mukherjee, Debasmita Chatterjee, Banhishikha Singh, Krishnendu Paira

Bibliographic record

VenueInternational Journal of Applied Biology · 2023
Typearticle
Languageen
FieldChemistry
TopicChromatography in Natural Products
Canadian institutionsBiotechnology Research Institute
Fundersnot available
KeywordsBiologyCaeruleaGallus gallus domesticusLotusBotanyImmune systemEmbryoLotus effectPathologicalZoologyImmunologyCell biologyEcologyMedicinePathology

Abstract

fetched live from OpenAlex

Nymphaea caerulea is an aquatic plant originally found in the Nile River has several therapeutic activities - anti-depressant, anti-inflammatory, anti-oxidant, and anti-microbial activities. This led us to perform the study focusing on the anti-microbial properties of the flower extract. Crude ethanolic extract of petals and pollens of N. caerulea flower were prepared and its antimicrobial activity was checked against E. coli. The Minimum Inhibition Concentration value was determined showing that both the extracts had similar capability against both the strains, with MIC value of 0.39mg/ml and 0.78mg/ml MIC against E.coli ATCC and MDR strains respectively. Further studies were done to study the gross morphological changes and the genetic expression changes of IL-10 and IFN-γ in E. coli-infected Gallus gallus domesticus embryo models. From the results, it can be said that the extract has preventive effects that reduce haemorrhages of the embryos when infected with E. coli. Moreover, there was slight increase in the level of IL-10 cytokine gene expression indicating its anti-inflammatory action along with a higher increase in the IFN-γ cytokine gene expressions responsible for activating the host immunity. Thus, the findings indicate the probable potential role of N. caerulea flower extract to act as an antibacterial agent.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.306
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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