Comparison of intraarticular corticosteroid and autologous platelet rich plasma injection in patients with knee osteoarthritis.
Why this work is in the frame
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Bibliographic record
Abstract
Objective: To compare IA corticosteroid and autologous PRP injection in OA knee, in terms of reducing stiffness, alleviating pain, and enhancing physical functionality. Study Design: Quasi-experimental study. Setting: AFIRM Rawalpindi. Period: Aug 2019 to April 2020. Methods: 70 patients with Knees OA, 40-70 years of age were included. Group A received IA 40 mg Triamcinolone Injection while Group B received PRP Injection in the affected knee. Pain evaluation was carried out using the Numerical Rating Scale (NRS) and the Western Ontario McMaster Osteoarthritis (WOMAC) Index at baseline, at 1 month, at 3rd month, and after 6 months and mean changes calculated. Results: Among 70 patients, 36 were male (52%) and 34 were female (48%). No notable differences were observed in age (p=0.210), sex (p=0.811), and body mass index (BMI) (p=0.985) between two groups. Pre-injection pain severity assessed on NRS (p=0.217) and OA severity assessed on WOMAC (p=0.010) differed not between the two groups. At 6 months postinjection, there was significant improvement (p-value < 0.05) in pain relief in Group B (IA PRP) compared to Group A (IA steroid injection). However, at 1 month post injection NRS and WOMAC has shown more improvement between Group A and Group B, a significant difference was observed (p < 0.0001). Conclusion: PRP Injection decreases joint pain and improve quality of life better than corticosteroid injection prolonged periods.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it