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Record W4403282015 · doi:10.1007/s40123-024-01042-6

What is Occluding Our Understanding of Retinal Vein Occlusion?

2024· article· en· W4403282015 on OpenAlexaff
Christiana Dinah, Andrew Chang, Junyeop Lee, William W. Li, Rishi P. Singh, Lihteh Wu, David T. Wong, Insaf Saffar

Bibliographic record

VenueOphthalmology and Therapy · 2024
Typearticle
Languageen
FieldMedicine
TopicRetinal and Optic Conditions
Canadian institutionsSt. Michael's Hospital
FundersF. Hoffmann-La RocheRoche
KeywordsMedicineOcclusionOphthalmologyRetinal VeinCentral retinal vein occlusionRetinalAnatomySurgeryMacular edema

Abstract

fetched live from OpenAlex

Retinal vein occlusion (RVO) remains a significant cause of visual impairment and is the second most common retinovascular disease after diabetic retinopathy [ 1 , 2 ]. Although the exact etiology remains elusive, RVO is thought to occur because of thrombus formation occluding the central, hemi-retinal, or branch retinal vein restricting normal blood flow and typically results in sudden, painless vision loss in the affected eye [ 1 , 2 , 3 , 4 , 5 ]. Despite first being described in the nineteenth century [ 1 ], and the advances in diagnostic modalities and novel therapies since, large gaps persist in our understanding of the pathophysiology and optimal management of RVO. Hence, the patient journey for RVO is not well defined [ 3 , 5 ].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.220
Threshold uncertainty score0.593

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.075
GPT teacher head0.363
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2024
Admission routes1
Has abstractyes

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