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Record W4403453860 · doi:10.1101/2024.10.15.24315420

A qualitative study exploring the diagnostic and treatment journeys of children and young people with gastroduodenal disorders of gut-brain interaction, their families, and the clinicians who care for them

2024· preprint· en· W4403453860 on OpenAlexaff
Gayl Humphrey, Mikaela Law, Celia Keane, Christopher N. Andrews, Armen A. Gharibans, Greg O’Grady

Bibliographic record

VenuemedRxiv · 2024
Typepreprint
Languageen
FieldMedicine
TopicEthics and Legal Issues in Pediatric Healthcare
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsQualitative researchMedicinePsychiatryPsychologyFamily medicineSociologySocial science

Abstract

fetched live from OpenAlex

Abstract Background Gastroduodenal disorders of gut-brain interaction (DGBI) are prevalent in the paediatric population. Diagnostic pathways and subsequent treatment management approaches for children and young people can be highly variable, leading to diverse patient and clinical experiences. This study explores the DGBI diagnostic experiences of children and their families and the perspectives of clinicians in the New Zealand context. Methods Semi-structured interviews were conducted with 12 children with gastroduodenal DGBIs and their families and clinicians who care for children with DGBIs. Interviews were recorded, transcribed, and narratively analysed. Results Five children and family themes emerged: 1) how it all started, 2) the impacts symptoms had on child and family life, 3) their experiences with testing and investigations, 4) the perceptions and impacts of challenging clinical relationships, and 5) the uncertainness of trial and error treatments. Clinicians also identified five key themes: 1) navigating the complexity of presenting symptomology, 2) the challenging diagnostic investigation decision-making process, 3) navigating management and treatment approaches, 4) a lack of standardised clinical pathways, and 5) establishing therapeutic relationships with patients and families. Conclusion Children, their families, and clinicians confirmed the clinical complexity of DGBIs, the challenges of diagnosis and management, and the stress this places on therapeutic relationships. Clearer diagnostic pathways and new investigations that could provide improved identification and discrimination of DGBIs are needed to minimise the treat-test repeat cycle of care and improve health outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.013
metaresearch head score (Gemma)0.020
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.026
Threshold uncertainty score0.069

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0130.020
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0130.010
Scholarly communication0.0040.005
Open science0.0020.006
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.385
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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