Psychiatric Disorders in Onconephrology Patients: Prevalence, Impact on Survival, and Quality of Life
Bibliographic record
Abstract
Background: Onconephrology has emerged as a crucial subspecialty. Psychiatric disorders are common in cancer and kidney patients, but their impact in Onconephrology patients is not known. The aims of study are to investigate the prevalence and impact of psychiatric disorders on survival and quality of life in Onconephrology patients. Methods: This prospective study included patients from the Onconephrology Unit (Nov-2021 to Feb-2023). Questionnaires assessed sleep disorders (Epworth scale), depression (GDS, PHQ), cognition (Montreal scale), and anxiety (GAD) at the first visit, 6 months, and 12 months. Clinical and analytical characteristics were collected. Results: 182 patients were included (mean age 68(±11) years, 70(38.5%) women). 18(9.9%) lived alone, 152(83.5%) lived accompanied and 4(2.2%) in residence. At the first visit, (81)44.5% had sleep disorders, 52(32.7%) depression, 72(39.6%) cognitive impairment, and 14(7.7%) anxiety. Depression was more prevalent in people who lived in residence (p=0.013). Patients with cognitive impairment had a higher prevalence of DM(p=0.003), worse kidney function and were older(p<0.001). Sleep disorders were more prevalent in older patients(p=0.01), and anxiety in women(p<0.001). At six months, anxiety was higher in women(p=0.03) and those with progressive oncological disease(p<0.001). Living alone was linked to more depression(p=0.002). At twelve months, depression correlated with oncological progression(p=0.034). Multivariate analysis identified age as a risk factor for cognitive impairment(OR: 1.1; p<0.001) and female sex for depression(OR: 3.39; p=0.001). At 6 months, female sex was a risk factor for anxiety(OR: 8.6; p=0.01) and living alone for depression(OR: 10.8; p<0.001). 30(16.5%) patients died during follow-up. Kaplan-Meier analysis showed higher mortality in patients with sleep disorders(p=0.039), worse kidney function(p=0.003), and progressive disease(p=0.028) Conclusion: Onconephrology patients had high rates of depression and anxiety, especially females and people living alone. Comprehensive approaches and early detection tools are essential to improve their survival and quality of life.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".