An unusual cause of upper gastrointestinal bleeding
Bibliographic record
Abstract
A 71-year-old gentleman presented with chronic dysphagia complicated by severe malnutrition secondary to a 1 cm length, 8 mm diameter recalcitrant distal oesophageal peptic stricture. This was on a background of spina bifida, alcohol dependence disorder, and neurogenic bladder requiring self-catheterization. Between 2016 and 2023, the patient underwent serial dilatations with limited clinical benefit. He was then referred for placement of an oesophageal metal stent. A 14 mm wide × 30 mm long Hanaro Plumber metal stent was then placed (Figure 1). Endoscopic views of a recalcitrant benign distal oesophageal stricture before and after deployment of a 14 mm wide × 30 mm long Hanaro Plumber metal stent. Fluoroscopic confirmation of successful metal stent deployment. Four days post-operatively, the patient returned with nausea and vomiting. Computed tomography (CT) did not identify a cause for his symptoms; however, the distance between the aorta and the oesophageal metal stent was 3.2 mm (Figure 2). Fourteen days post-operatively, the patient developed haematemesis complicated by severe hypotension requiring massive transfusion activation. An EGD revealed a large clot arising from within the oesophageal metal stent without a clear treatable target. A CT angiogram confirmed an aortic injury with pseudoaneurysm formation and active extravasation into the proximal stomach (Figure 3). Emergent thoracic endovascular repair was undertaken (Figure 4) and hemostasis was achieved. Despite successful hemostasis, the patient passed away 2 days later from multi-organ failure. Thoracic and abdominal computed tomography confirming no oesophageal stent migration or cause for the patient’s nausea and vomiting. Peri-aortic haematoma and lobulated pseudoaneurysm; oesophageal stent and aorta. Nipple-like outpouching from aortic injury with active arterial extravasation. Thoracic endovascular aortic repair with successful placement of a 26 mm × 10 cm thoracic endograft with no contrast leak. The oesophageal stent is seen adjacent. There are a small number of case reports that describe oesophageal stent-related aorto-oesophageal fistula (AEF) formation.1–4 Proposed risk factors include prior repeated dilatations, radiotherapy, or proximal stricture location.3,4 In our case, the bi-flanged metal stent may have also increased the risk of AEF formation secondary to local compression of the oesophageal mucosa. CT angiogram is the gold standard for diagnosis.5 AEF-associated mortality is approximately 75% with intervention and 100% without intervention.5 Prompt recognition of AEF to facilitate urgent intervention is therefore paramount. T.H. (Literature review, Data acquisition, Drafting of the manuscript), G.M. (Conceptualization, Supervision, and Revision of manuscript), C.T. (Conceptualization, Supervision, and Revision of manuscript) None declared. Conflict of interest disclosure forms (ICMJE) have been collected for all co-authors and can be accessed as supplementary material here. The data are only of one patient. There are no other data associated with this manuscript.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.009 |
| Meta-epidemiology (narrow) | 0.003 | 0.002 |
| Meta-epidemiology (broad) | 0.002 | 0.002 |
| Bibliometrics | 0.007 | 0.004 |
| Science and technology studies | 0.005 | 0.003 |
| Scholarly communication | 0.004 | 0.003 |
| Open science | 0.003 | 0.003 |
| Research integrity | 0.012 | 0.007 |
| Insufficient payload (model declined to judge) | 0.005 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".