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Late Breaking Abstract - In-vitro evaluation of a neonatal adaptation of an adult oscillometer for respiratory mechanics assessment

2024· article· en· W4404097598 on OpenAlexaff
Davide Bizzotto, Pasquale Pio Pompilio, Alessandro Gobbi, Raffaele L. Dellacá

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicRespiratory Support and Mechanisms
Canadian institutionsOptech (Canada)
Fundersnot available
KeywordsAdaptation (eye)Computer scienceRespiratory physiologyRespiratory systemMedicinePsychologyNeuroscienceInternal medicine

Abstract

fetched live from OpenAlex

Aim: Respiratory oscillometry assesses respiratory mechanics independently of patient efforts. Existing commercially-available oscillometry devices are designed for children aged > 3yrs, preventing their use in neonatal care. We aimed to evaluate the in-vitro accuracy of a novel oscillometer that addresses specific neonatal requirements such as very low dead space and highly accurate flow sensing. Methods: A Resmon PRO FULL oscillometer (RESTECH Srl) was modified by connecting a breathing circuit tube, an intentional leak, proximal flow and pressure sensor and a neonatal face mask to the device patient connector, resulting in a dead space <1.5 ml/kg with a bias flow of 8 L/min for CO2 washout. An active test lung made of mesh-type resistors (15, 25, and 40 cmH2Os/l) to simulate airway resistance (Rrs) and acrylic glass cylinders (0.5, 1.0, and 3 L) to simulate reactance (Xrs) was configured to replicate spontaneous neonatal breathing patterns. Measured respiratory impedance at 8 and 10 Hz were compared with theoretical values (Franken et al., 1981). Results: Rrs and Xrs at 8 and 10 Hz closely matched expected values, as for breathing pattern metrics, with measurements errors staying within the recommended limits (Table). Conclusion: The modified oscillometer accurately measures respiratory impedance and breathing pattern indexes in in-vitro models of infants from 2.5 kg to approximately three years old. erj;64/suppl_68/PA4086/F1 F1 F1

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.074
GPT teacher head0.376
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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