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Inspiration: two decoupled diaphragms

2024· article· en· W4404100859 on OpenAlexaff
Giovanni Tagliabue, Michael Ji, Danny J. Zuege, Paul A. Easton

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldNeuroscience
TopicNeuroscience of respiration and sleep
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsComputer science

Abstract

fetched live from OpenAlex

INTRODUCTION Although inspiratory airflow is generated primarily by the diaphragm, costal (COS) and crural (CRU) diaphragm have distinct neural-mechanical profiles and varying mechanical advantage. QUESTION Do COS and CRU make equivalent contributions to generation of inspiratory airflow? METHODS Data N=12 canines, from database completed in 2009, implanted with sonomicrometers and EMG electrodes into left COS and CRU. After recovery, while awake, airflow, muscle length and moving average EMG were recorded during room air and CO2 stimulation, analyzed breath by breath and expressed as percent of maximum at successive 5% "slices" of TTOT(%TTOT). RESULTS At room air, mechanical contributions of COS and CRU were significantly different (p<0.05), with COS progressively diverging to greater contribution than CRU (Figure 1). Peak EMG of COS and CRU did not occur at peak inspiratory airflow, but much later in inspiration. And the segments were asynchronous, with peak CRU EMG occurring consistently after COS (p<0.05) (Figure 2). CONCLUSIONS COS and CRU contributions to inspiratory airflow are significantly different, EMG activation is not in phase with inspiratory airflow, and segmental activity is asynchronous. erj;64/suppl_68/PA1664/F1 F1 F1 erj;64/suppl_68/PA1664/F2 F2 F2

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.024

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.325
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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