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Evaluating the relationship between respiratory muscle electromyography and ultrasound in healthy subjects

2024· article· en· W4404102167 on OpenAlexaff
Annalisa Frizzelli, Junyi Zhang, Owais Kadwani, Alfredo Chetta, Georgios Kaltsakas, Rebecca D’Cruz

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicInfrared Thermography in Medicine
Canadian institutionsSt. Thomas Hospital
Fundersnot available
KeywordsElectromyographyUltrasoundRespiratory systemPhysical medicine and rehabilitationMedicineComputer scienceInternal medicineRadiology

Abstract

fetched live from OpenAlex

Introduction: Respiratory muscle function may be evaluated using non-invasive tests, including parasternal or diaphragm surface electromyography (EMGpara, EMGdi) and thoracic ultrasound (US). The relationship between respiratory muscle EMG and US indices has not previously been evaluated. Methods: Healthy subjects performed spirometry, sniff, maximal inspiratory and expiratory mouth pressures (SNIP, MIP, MEP). Tidal and sniff USdi excursion and end-tidal inspiratory parasternal thickness were assessed. EMGpara and US-guided EMGdi were performed to measure neural respiratory drive index (NRDI). Data are reported as mean (±SD) or median (IQR). Pearson or Spearman correlation analyses were performed as appropriate. Results: Twenty subjects (12 females, mean age 33.45±8.97 years) had: FEV1 99±12%pred, FVC 102±13%pred, SNIP 89±30 cmH2O, MIP 86±35 cmH2O, MEP 102±47 cmH2O. NRDIpara was 113 (59-251)%·bpm and NRDIdi was 90 (40-184)%·bpm. Sniff USdi excursion was 2.48 (1.90-2.90) cm, tidal USdi was ­­­­­­1.97 (1.47-2.10) cm. Right and left parasternal thickness were 0.36±0.15 and 0.33±0.14 cm, respectively. Inverse correlations were found between NRDIpara and sniff USdi excursion (r=-0.58, p=0.01) and SNIP (r=-0.69, p=0.001), and NRDIdi and sniff USdi (r=-0.45, p=0.04) and SNIP (r=-0.46, p=0.04). SNIP was positively correlated to sniff USdi excursion (r=0.57, p=0.01). Conclusion: In healthy subjects, surface electromyography of parasternal intercostal muscles and diaphragm is related to US-measured diaphragm excursion. Evaluation of these non-invasive tests of respiratory muscle function in disease states where there is load capacity imbalance of the respiratory muscle pump is warranted.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.097
GPT teacher head0.398
Teacher spread0.301 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2024
Admission routes1
Has abstractyes

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