Home-based physical activity in ILD: an RCT
Bibliographic record
Abstract
Home-based physical activity (PA) in interstitial lung disease (ILD) may be fundamental to tackle physical inactivity. We explored the efficacy and effectiveness of the Lifestyle Integrated Functional Exercise for people with ILD (iLiFE) trial ( NCT04224233 ). An RCT, assessor blinded, was conducted. After the baseline assessment, participants were randomly assigned to the experimental (EG: iLiFE-12-weeks of a home-based PA programme embedded in individuals’ daily routines) or the control (CG: usual care) group. Data were collected before and immediately after iLiFE. Primary outcome was PA (steps/day, time spent in moderate to vigorous PA [MVPA]/day/week). Secondary outcomes were symptoms, muscle strength, functional status, emotional function, healthcare utilisation, exacerbations and falls. Efficacy and effectiveness were assessed using intention-to-treat and per-protocol analysis with linear mixed methods. We included 48 participants (54% female, 67±11yrs, DLCO%p 50±17; nEG/nCG=24/24). Interaction group*time showed that iLiFE was efficacious and effective in maintaining PA levels and in improving muscle strength, functional status and health-related quality of life (p<0.05) in people with ILD (Fig. 1). No other significant interactions were observed. No adverse events were reported. iLiFE is an efficacious and effective intervention to maintain PA levels and improve other health-related domains in people with ILD and may now be considered to improve ILD management. erj;64/suppl_68/OA942/F1 F1 F1
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.010 | 0.012 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.003 | 0.004 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.003 | 0.002 |
| Insufficient payload (model declined to judge) | 0.006 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".