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The Revival of Cholera Vaccines: The Century-Old Making of a Global Success Story

2024· article· en· W4404120672 on OpenAlexvenueno aff
Leonardo W Heyerdahl

Bibliographic record

VenueAnthropologica · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicVibrio bacteria research studies
Canadian institutionsnot available
Fundersnot available
KeywordsCholeraHistoryPolitical scienceMedicineVirology

Abstract

fetched live from OpenAlex

Cholera vaccines have existed since the nineteenth century but were largely considered an ineffective control strategy for much of their history. However, in 2012, cholera vaccination campaigns were piloted in Haiti and Guinea using a preexisting vaccine formula. These initial efforts quickly expanded to dozens of countries. A global stockpile of millions of doses was established, positioning cholera vaccines as a cornerstone to the Global Task Force on Cholera Control’s Roadmap to ending cholera by 2030. What factors contributed to this remarkable turnaround? This piece explores the epistemic, moral, and industrial reconfigurations that sustained the crafting of a global vaccine success story and its ramifications within a shifting global health landscape, including the potential displacement of water and sanitation interventions. The research is based on my participation in cholera vaccine introductions as a medical NGO worker and on symmetric ethnographic fieldwork conducted in African settings targeted for reactive cholera vaccination and in global North centers influencing global cholera vaccine policy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.992
Threshold uncertainty score0.047

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0090.010
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0080.044
Scholarly communication0.0120.018
Open science0.0010.009
Research integrity0.0040.009
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.345
Teacher spread0.329 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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