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Enhancing data standards to advance translation in spinal cord injury

2024· review· en· W4404171762 on OpenAlexafffund
Vanessa K. Noonan, Suzanne Humphreys, Fin Biering‐Sørensen, Susan Charlifue, Yuying Chen, James D. Guest, Linda Jones, Jennifer French, Eva Widerström-Noga, Vance Lemmon, Allen W. Heinemann, Jan M. Schwab, Aaron A. Phillips, Marzieh Mussavi Rizi, John L. K. Kramer, Catherine R. Jutzeler, Abel Torres‐Espín

Bibliographic record

VenueExperimental Neurology · 2024
Typereview
Languageen
FieldMedicine
TopicArtificial Intelligence in Healthcare and Education
Canadian institutionsUniversity of WaterlooLibin Cardiovascular Institute of AlbertaPraxis Spinal Cord InstituteInternational Collaboration On Repair Discoveries
FundersNational Institute of Neurological Disorders and StrokeGovernment of Canada
KeywordsInteroperabilityData sharingSpinal cord injuryComputer scienceBig dataData scienceAnalyticsData managementMedicineData miningWorld Wide Web

Abstract

fetched live from OpenAlex

Data standards are available for spinal cord injury (SCI). The International SCI Data Sets were created in 2002 and there are currently 27 freely available. In 2014 the National Institute of Neurological Disorders and Stroke developed clinical common data elements to promote clinical data sharing in SCI. The objective of this paper is to provide an overview of SCI data standards, describe learnings from the traumatic brain injury (TBI) field using data to enhance research and care, and discuss future opportunities in SCI. Given the complexity of SCI, frameworks such as a systems medicine approach and Big Data perspective have been advanced. Implementation of these frameworks require multi-modal data and a shift towards open science and principles such as requiring data to be FAIR (Findable, Accessible, Interoperable and Reusable). Advanced analytics such as artificial intelligence require data to be interoperable so data can be exchanged among different technology systems and software applications. The TBI field has multiple ongoing initiatives to promote sharing and data reuse for both pre-clinical and clinical studies, which is an opportunity for the SCI field given these injuries can often occur concomitantly. The adoption of interoperable standards, data sharing, open science, and the use of advanced analytics in SCI is needed to facilitate translation in research and care. It is critical that people with lived experience are engaged to ensure data are relevant and enhances quality of life.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.145
metaresearch head score (Gemma)0.268
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.855
Threshold uncertainty score0.767

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1450.268
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0100.011
Science and technology studies0.0040.009
Scholarly communication0.0170.043
Open science0.0050.026
Research integrity0.0070.010
Insufficient payload (model declined to judge)0.0090.007

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.316
GPT teacher head0.583
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainReporting
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations5
Published2024
Admission routes2
Has abstractyes

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