MétaCan
Menu
Back to cohort
Record W4404282935 · doi:10.1016/j.net.2024.11.013

A comparative dosimetric evaluation of dynamic conformal arc therapy and volumetric modulated arc therapy for lung stereotactic body radiotherapy

2024· article· en· W4404282935 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueNuclear Engineering and Technology · 2024
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsPrincess Margaret Cancer CentreUniversity of Toronto
Fundersnot available
KeywordsRadiation therapyMedicineStereotactic radiotherapyLungArc (geometry)Nuclear medicineRadiologyInternal medicineMathematicsRadiosurgery

Abstract

fetched live from OpenAlex

This study assesses the viability of utilizing dynamic conformal arc therapy (DCAT) as an alternative to volumetric-modulated arc therapy (VMAT) in stereotactic body radiation therapy (SBRT) for lung cancer, with a focus on four-dimensional computed tomography (4DCT) in free-breathing conditions. We selected four non-small cell lung cancer (NSCLC) patients who had previously undergone VMAT SBRT and re-planned their treatment using DCAT. We compared the DCAT and VMAT plans based on dose distribution, conformity index (CI), homogeneity index (HI), gradient index (GI), and total monitor units (MUs). Quality assurance (QA) assessments for both plans were conducted using the Octavius 4D system (PTW, Freiburg, Germany). The results showed that CI Paddick was 0.80 ± 0.06 and 0.79 ± 0.04 (p-value >0.05), HI was 1.16 ± 0.03 (p-value <0.05) and 1.07 ± 0.02, GI was 3.91 ± 0.05 and 3.40 ± 0.05 (p-value <0.05), and MU was 1880.42 ± 135.19 and 5020.82 ± 188.03 for DCAT and VMAT, respectively (p-value <0.05). The average gamma passing rate exceeded 95 % with a 2 %/2 mm criteria. The dose distribution displayed remarkable similarity between DCAT and VMAT. The DCAT technique exhibits the capacity to deliver PTV dose distributions comparable to those achieved with VMAT, while significantly reducing treatment duration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.985
Threshold uncertainty score0.765

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.287
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it