Twilight in the emergency department: Porphyria, mad kings, vampires and werewolves? A brief review
Bibliographic record
Abstract
OverviewThe porphyrias are a group of disorders of the heme biosynthesis pathway (also known as the porphyrin pathway) that present with acute neurovisceral symptoms or skin lesions or both.Diagnosis is difficult and they are often missed or wrongly diagnosed (Thadani, Deacon, & Peters, 2000).Acute attacks may present with symptoms including severe abdominal pain (Anderson et al., 2005), hysteria (Millward, Kelly, King, & Peters, 2005), and motor neuropathies (weakness).As there is a very characteristic discrepancy between the serious complaints and the actual clinical findings, these patients can present a challenge to the emergency nurse (Liu et al., 2005;Tasnadi, Bor, Pusztai, & Szekely, 2003).The name porphyria is derived from the Greek o, porphyra, "purple pigment".The name is believed to have been a reference to the purple discolouration of feces and urine in patients during an attack (Lane, 2002).Porphyrias are classified as acute (also known as hepatic) or chronic (also described as cutaneous or erythropoietic) (Forbes & Jackson, 1997).
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".