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“‘latex Do myomectomies alter third-trimester complications compared to women without myomectomies and uterine fibroids in situ: A retrospective cohort study of an American population database.

2024· preprint· en· W4404338631 on OpenAlexaff
Perrine Ginod, Ahmad Badeghiesh, Haitham Baghlaf, Michael H. Dahan

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldMedicine
TopicUterine Myomas and Treatments
Canadian institutionsMcGill University Health Centre
Fundersnot available
KeywordsMedicinePlacenta previaObstetricsUterine ruptureRetrospective cohort studyGestational diabetesHysterectomyUterine fibroidsPregnancyPopulationGynecologyOdds ratioGestationFetusUterusSurgeryPlacentaInternal medicine

Abstract

fetched live from OpenAlex

Objective: To evaluate population characteristics and obstetrical complications post-myomectomy vs. fibroids in situ. Design: Retrospective cohort study. Setting: Hospital discharges from the Healthcare Cost and Utilization Project Nationwide Inpatient Sample (2004-2014). Population: 14,206 pregnancies post-myomectomy and 81,517 with fibroids in situ. Methods: Multivariate logistic regression with adjustment. Main Outcome Measures: Pregnancy, delivery, and neonatal outcomes. Results: Post-myomectomy patients were younger, with lower BMIs, higher IVF use, more commonly Caucasians or Hispanics, and had higher rates of pregestational diabetes, smoking, illicit drug use, previous cesarean delivery, and multiple gestations, compared to the in situ fibroids group. Post-myomectomy patients had decreased rates of gestational hypertension (aOR 0.87, 95%CI 0.77-0.97), eclampsia (aOR 0.76, 95%CI 0.32-0.81), gestational diabetes (aOR 0.83, 95%CI 0.77-0.90), spontaneous vaginal deliveries (aOR 0.09, 95%CI 0.08-0.11), postpartum hemorrhage (aOR 0.77, 95%CI 0.68-0.88), and intra-uterine fetal death (aOR 0.64, 95%CI 0.43-0.97). Conversely, they had increased risks of placenta previa (aOR 1.40, 95%CI 1.20-1.64), preterm delivery (aOR 1.16, 95%CI 1.07-1.24), cesarean section (aOR 8.64, 95%CI 7.71-9.69), uterine rupture (aOR 2.21, 95%CI 1.31-3.74), transfusions (aOR 1.79, 95%CI 1.59-2.02), and congenital anomalies (aOR 2.35, 95%CI 2.01-2.75). Conclusions: The in situ fibroid group experienced different complications than the post-myomectomy group. Pregnancies post-myomectomies could benefit from additional screening or interventions during pregnancy to reduce complications from malplacentation and ensure delivery in specialized centers to mitigate risks. Patients should be counseled regarding these potential risks. Increased understanding of the role of myomectomies on reproductive outcomes requires further prospective studies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.343
Teacher spread0.323 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2024
Admission routes1
Has abstractyes

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