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Record W4404367375 · doi:10.4271/09-12-02-0011

Intracranial Displacements due to Blunt Force Impact in a Postmortem Human Surrogate Brain

2024· article· en· W4404367375 on OpenAlexaff
Jean-Jacques Demiannay, Jennifer Rovt, MacKenzie Brannen, Sheng Jun Xu, Gia Kang, Ashley Yip, Amir Hossein Azadi, Parisa Dehghan, Shannon Goodwin, Reggie Taylor, Katherine Poon, Susan Brien, Blaine Hoshizaki, Clara Karton, Oren E. Petel

Bibliographic record

VenueSAE International Journal of Transportation Safety · 2024
Typearticle
Languageen
FieldMedicine
TopicAutomotive and Human Injury Biomechanics
Canadian institutionsHorizon Health NetworkClinique Neuro-OutaouaisRoyal Ottawa Mental Health CentreUniversity of OttawaCarleton University
Fundersnot available
KeywordsBluntSurrogate endpointTraumatic brain injuryMedicineSurgeryRadiologyPsychiatry

Abstract

fetched live from OpenAlex

<div>Prevention and diagnosis of traumatic brain injuries (TBI) are reliant on understanding the biomechanical response of the brain to external stimuli. Finite element models (FEM) and artificial head surrogates are becoming a common method of investigating the dynamic response of the brain to injurious impact and inertial stimuli. The accuracy and validity of these models is reliant on postmortem human subject (PMHS) research to produce biofidelic brain tissue responses. Previous PMHS research has been performed to measure intracranial pressures, displacements, and strains when subjected to impact and inertial loading; however, there remains a need for additional PMHS datasets to improve our understanding of the brain’s dynamics. The purpose of this study is to measure the relative brain–skull displacement in a PMHS specimen when subjected to blunt force impacts. A high-speed X-ray (HSXR) imaging system and embedded radiopaque elastomeric markers were used to record PMHS impacts at varying impact velocities for two specimens: specimen CO-108 was subjected to a series of frontal impacts and specimen CO-109 was subjected to a series of rear impacts. Brain–skull relative deformation in each specimen indicates that brain deformation is dependent both on anatomical regions and of impact direction.</div>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.816
Threshold uncertainty score0.788

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.349
Teacher spread0.336 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueSAE International Journal of Transportation SafetySame topicAutomotive and Human Injury BiomechanicsFrench-language works237,207