Anorexia Nervosa in Comorbidity With Borderline Personality Disorder in Adolescence: A Specific Clinical Endophenotype?
Why this work is in the frame
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Bibliographic record
Abstract
OBJECTIVE: Anorexia nervosa and borderline personality disorder are often associated and share some core elements, including emotional dysregulation and affective instability. Nevertheless, the association of these two conditions in adolescence is still little studied. METHOD: The present study aims at investigating, through a multidimensional assessment, the psychopathological characteristics of adolescents affected by anorexia nervosa in comorbidity with borderline personality disorder on a sample of 127 female adolescents, through the comparison with adolescents with borderline personality disorders and adolescents with anorexia nervosa. All participants completed a validated psychometric battery assessing alexithymia (Toronto Alexithymia Scale-20), depression (Children's Depression Inventory), psychological symptoms (Symptom Checklist-90-Revised) and psychological symptoms relevant in eating disorders (Eating Disorders Inventory-3). RESULTS: Adolescents with anorexia nervosa in comorbidity with borderline personality disorder show intermediate features between the two disorders individually in the general psychopathological profile, but a peculiar psychological profile regarding the eating symptomatology, with worse features compared to adolescents with the sole anorexia nervosa. CONCLUSIONS: Results suggest a peculiar clinical and psychopatological endophenotype in adolescents with anorexia nervosa in comorbidity with borderline personality disorders, indicating the need to define specific and tailored treatment for this population.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it